It has a one of the quick growing incidence rates in the United States. Barrett's Esophagus can lead to adenocarcinoma. Key Aspects Repeated Biopsies: There is a possibility of change of treatment when the biopsies are repeatedly done. Delayed Treatment: Treatment is delayed till the next endoscopy procedure. Limited Adherence: If the adherence to guidelines are limited, cancer detection becomes inefficient. Endoscopic Eradication: Barrett's Esophagus of endoscopic eradication is complex and evolving.