Helicobacter pylori infection is one of the most abundant bacterial infections all over the world. Only total eradication of the pathogen effectively protects from gastritis as well as from gastric and duodenal ulcers. If an infection is suspected a C-breath test with its high sensitivity and specificity nowadays is the golden standard for detecting this insidious germ. Additionally, it is the most pleasant method because not the individual person but only his/her breath is investigated. The troublesome swallowing of a tube can be reduced to a minimum.