The AB SCIEX TripleTOF® 4600 System makes routine high-resolution accurate mass MS and MS/MS available to any laboratory. Built on the innovative breakthrough in LC/MS/MS performance of the original TripleTOF 5600, it uniquely integrates comprehensive qualitative exploration, rapid profiling, and high-resolution quantitation workflows on a single platform. TripleTOF 4600 combines the highest sensitivity detection in its class and high-resolution with at least 3X better acquisition speed, and stable ~2ppm mass accuracy over days of acquisition. High resolution at unparalleled speed - up to 30,000 FWHM with 10 msec accumulation time Highest sensitivity in class - lowest limits of quantitation (LOQ) for a high resolution system and equivalent to high-performance triple quads SmartSpeedTM 100Hz Acquisition delivering high-resolution for high-speed chromatography - up to 100 spectra in a second or 50 spectra in a second while maintaining intelligent real-time data filtering (IDA) EasyMassTM Accuracy without continuous recalibration - over 50 hours of continuous LC/MS operation provides <2 ppm RMS