Capillary Electrophoresis (CE) offers fast separations with exceptional efficiency and resolution for analytical challenges that often can only be met with difficulty by LC. Used in standalone mode, as the separations component of a CE/MS, or as a complementary, orthogonal technology to LC, the new Agilent 7100 CE system brings unprecedented HPLC-like sensitivity to a wide range of analytical challenges. In addition, CE offers the advantage that several separation modes can be run on a single instrument. This makes CE a very versatile technique for a broad range of applications and separation challenges.