The TOX.I.S. is a solution that helps to identify drugs in body fluids. The toxicological analysis of body fluids is an essential task, as the consumption of illicit drugs needs to be identified. The analysis also requires a lot of effort, as the pretreatment and identification methods are called and have to be done as soon as possible. This prominent HPLC system with photodiodearray detection configured as exclusive solution system offers identification based on factors such as retention time and the UV spectra of the component. The system is based on hardware modules using a unique column switching procedure to allow sample pretreatment for urine samples. It also features a cleaning step, which includes rinsing to get rid of the urine components. The sample can be transferred onto the analytical columns.