Orsiro is a one of a kind solution for the treatment of coronary artery stenosis. It has a PROBIO passive coating which encloses the metal stent keeping it from interacting with the encompassing tissue and preventing it from any unnecessary contact. On the other hand, the BIOlute® is the active component of the stent. It is made of a combination of bioabsorbable polymer matrix and a Limus drug which makes possible a regulated drug release. Since the BIOlute® is bioabsorbable, what remains in a patient is a PROBIO-coated stent. Orsiro is considered a sixth generation coronary bare metal stent as it uses PRO-Kinetic Energy as its platfrom. It is strong and radiopaque as it is made of a cobolt chromium alloy, allowing thinner struts. Struts as thin as 60 µm makes the stent extra flexible in even the hardest to penetrate veins.