Creating Medical Nanorobots
Information about this project has been published in the journal Nature Nanotechnology. The research is based on the idea of computing using biomolecules. This is because many scientists believe that logical operations inside a cell or in an artificial bimolecular system control biological processes and this could thus be an effective way of creating micro- and nanorobots. These robots could be used for a variety of purposes such as delivering drugs on schedule to those tissues where they might be needed.
According to Maxim Nikitin, a 2010 graduate of MIPT's Department of Biological and Medical Physics and the lead author of this study, calculations using biomolecules inside cells is a promising and rapidly developing branch of science.
Biocomputing uses natural cellular mechanisms. This particular study focuses on extracellular biocomputing and could pave the way for a number of biomedical technologies. In addition, this particular study differs from previous projects in biocomputing because this is the first time a team has proposed and experimentally confirmed a method to transform any type of nanoparticle or microparticle into autonomous biocomputing structures that have the capability to implement a functionally complete set of Boolean logic gates and can bind to target through computation. In addition, this new research uses nanoparticles (of 100nn) and microparticles (3000nm or 3 micrometres) because it is believed that the smaller the size of the particle, the greater its reactivity.
During this study, the researchers coated the nanoparticles with a special layer which disintegrated in different ways when exposed to various combinations of signals. In order to bond the nanoparticles, the researchers selected antibodies. This is a new measure as most previous studies used DNA or RNA for logical operations. By using this method, the research team was able to show that cancer cells could be specifically targeted. In other words, the additional control derived through this technique could help in the accurate destruction of cancer cells with minimal impact on healthy tissues and organs. The team obtained both nanoparticles that could bind to different types of cells as well as particles that look for target cells when both of two conditions are met or when two different molecules are absent or present.
According to Nikitin, while this study is only a small step toward the creation of efficient nanobiorobots, it is a very interesting area of science and opens us new avenues for further research.
Source: Science Daily
Image credit: Wikimedia Commons
Published on : Mon, 25 Aug 2014
Print as PDF
Key FeaturesWe can provide an impressive range of clinical tools and deliver a remarkable clinical experience. On your PACS, off your PACS, within the surgical suite and beyond, iNtuition ensures your workflow is seamless and your imaging costs are minimized....
WHAT YOU SEE IS WHAT YOU GET3D Advanced Visualization is at the core of TeraRecon DNA. We are extending our capability to the 3D printing world with a dedicated image processing workflow to enhance 3D printing outcomes. Printing your model is easier...
Our iNtuition iEMV viewer can display many types of images. It can even do some pretty amazingly advanced things. As a leader in advanced visualization, you can trust that TeraRecon can deliver impressive capabilities, but we strive to make it simple,...
We can work across many PACS systems. No matter the size of your organization, iNtuition iReview can help you look across your imaging archives and create a unified interpretation view that’s made just for you. The configurable display protocols and user...