ICU Management & Practice, ICU Volume 9 - Issue 1 - Spring 2009

Will scientists one day be able to slow the aging of the brain and prevent diseases such as Alzheimer's and Parkinson's? Perhaps -- at least once the genetic coding associated with neuronal degeneration has been unraveled.


According to a new study published in The Journal of Neuroscience, a research team from the Université de Montréal, Maisonneuve-Rosemont Hospital and Lawrence Berkeley National Laboratory have identified a mutation in mice that dramatically accelerates the process of aging in the brain and the eye. The new study reveals that neurons in the retina and cerebral cortex require a gene called Bmi1 to prevent activation of the p53 pathway and the accumulation of free radicals.

 

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References:

University of Montreal. "Scientists Discover Gene Responsible For Brain's Aging." www.sciencedaily.com (January 18, 2009)