Editorial

Multiple factors can bring the microbiome out of balance in critically ill patients in the intensive care unit. These include antibiotic use, mechanical ventilation, changes in diet and inflammatory responses. The dysbiosis of the microbiome can alter immunological responses and could potentially have an impact on patient outcomes. There are approximately 100 billion microorganisms in our body. The micro

Point-of-View

Monitoring the strength of the patient´s breathing effort, titrating the sedation, and selecting the correct mode of ventilation is vital when transitioning from controlled to assisted ventilation. Assessing The Transition From Fully Controlled to Assisted Ventilation One of the key issues with mechanical ventilation is the transition from fully controlled to assisted mechanical ventilation, which must b

In 2020, the ultra-short acting beta-blocker landiolol was first included in the ESC guidelines with a class I recommendation. The recommendations were based on study results demonstrating the rapid response, efficacy, and safety of this drug. At a recent symposium, during 2021 Heart Failure World Congress, cardiologists were invited to present their daily clinical practice of landiolol use. The discover

Cover Story

Bacteria play a fundamental role in human life. Given the many roles of gut microbiota in critical illness and other pathological conditions, it is important to target therapeutical interventions to restore, preserve and enrich its composition. Introduction Bacteria play, for better or worse, a fundamental role in human life. As multidrug resistant bacterial infections are increasing in incidence and mort

Critical illness alters the intestinal microbiome, resulting in a loss of microbial diversity and induction of a pathobiome. Manipulating the intestinal microbiome offers a potential treatment approach in ICU patients. The intestinal microbiome is comprised of diverse, robust microbial communities within the intestine, modified by the host’s interaction with the environment (Amon and Sanderson 2017). I

A significant research gap exists in the field of the lung microbiome and pneumonia development in paediatric population. Its study may improve nosocomial pneumonia prevention and help to achieve zero pneumonia rates. Most frequent hospital acquired infections (HAI) in Paediatric Intensive Care Units (PICU), are ventilator associated pneumonia (VAP), catheter-related urinary tract infection and catheter-

The microbiota is recognised as one of the most important factors that can worsen the clinical conditions of patients who are already very frail in the intensive care unit. It also plays a crucial role in the prevention of ICU associated complications. It’s important to ensure the best functioning of the intestinal immune system. The gastrointestinal tract represents one of the barriers between the ext

Clostridioides difficile (C. difficile) infection is a potentially serious complication in critical patients admitted to the Intensive Care Unit (ICU). It generally occurs because of an alteration of the intestinal microbiota due to antibiotic exposure that must be timely identified and diagnosed to start proper and early management. Clostridioides difficile (C. difficile) is a Gram-positive anaerobic, s

Dysbiosis has been closely related to inflammation and severe-to-critical COVID-19, a reason why nutritional therapy could be important in the prevention and management of critical disease. Introduction Infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease (COVID-19), involves the recognition of the cell’s angiotensin converting enzyme 2 (ACE2) r

Matrix

What We Learned During the COVID-19 Pandemic That Should Not Be Forgotten An overview of the available evidence on safe intubation practices in critically ill patients in light of new discoveries due to the coronavirus pandemic. Introduction Orotracheal intubation is a life-saving procedure in critically ill patients with acute respiratory failure, but complications during the procedure are frequent and

Post-operative cardiac surgical patients are encountered commonly in the intensive care unit. Methylene blue might be a useful treatment for patients with vasopressor-refractory vasoplegia but high quality evidence is lacking. Cardiac surgery is one of the most frequently performed major surgical procedures, with more than 1 million operations annually. Major cardiac surgery requiring cardiopulmonary bypa

DigiConf

Join our panellists on October 12 at 16:00 CET as they discuss the role of microbiome in critical illness, possible complications and potential microbiome treatment strategies and approaches. Register here! Moderator JEAN-LOUIS VINCENT Editor-in-Chief ICU Management & Practice Professor Department of Intensive Care Erasme Hospital Université libre de Bruxelles Brussels, Belgium Panellists: FRANC

Agenda

OCTOBER 3-6 ESICM 34th Annual Congress, LIVES 2021 Virtual event https://iii.hm/1c6i 7-9 10th Europaediatrics 2021 Hybrid event, Zagreb, Croatia https://iii.hm/1c6j 8-12 ANESTHESIOLOGY 2021 Annual Meeting San Diego, USA https://iii.hm/1c6k 12-15 44th Annual Conference on Shock 2021 Portland, USA https://iii.hm/1c6l 25-28 ACEP 2021 - American College of Emergency Physicians Boston, USA https://iii.hm



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