• Polytrauma and Organ Crosstalk

    Authors Dieter G. Weber, MBBS, FRACS Department of Traumatology, Division of Surgery John Hunter Hospital and University of Newcastle Newcastle NSW, Australia Zsolt J. Balogh,   MD, PhD, FRACS, FACS Department of Traumatology, Division of Surgery John Hunter Hospital and University of Newcastle Newcastle,NSW, Australia [email protected]...

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  • How to Understand Organ-Organ Interactions

    A Compartment Syndrome (CS) is Defined as Increased Pressure in a Closed anatomic space which threatens the viability of enclosed and surrounding tissue (Malbrain et al. 2006). Within the body there are four major compartments: the head, the chest, the abdomen and the extremities. Within each compartment, individual organs can be affected...

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  • The Future of Glucose Control in the ICU

    Continuous glucose monitoring systems and therapeutic algorithms adapted to the actual insulin sensitivity are needed to prevent hypoglycaemia, hyperglycaemia and high glucose variability, all associated with poor outcome in intensive care unit (ICU) patients....

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  • Nutritional Failure: An Adaptive Response to Critical Illness?

    For decades, intensive care unit (ICU) physicians have been administering artificial nutrition to improve recovery and outcome. This intensified nutritional support has been associated with a better outcome in several large observational studies (Alberda et al. 2009), though unfortunately, it is impossible to distinguish cause and consequence by association....

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  • Challenges in Critical Care in Africa: Perspectives and Solutions

    Critical care medicine in Africa is largely an unknown entity in the medical world, though it has recently begun to emerge as a prominent concern, mostly due to increasing research that has highlighted the plight of this sub-specialty in Africa (Adhikari et al., 2010, Riviello et al., 2011). However, the fact that critical care medicine is considered...

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  • Improving Obstetrical Critical Care in Developing Nations

    A Thematic Review of Challenges and Solutions ringing down maternal morbidity and mortality rates and thereby improving reproductive health services has been a major concern in developing nations for the past few decades. In spite of adopting on the various measures and implementing new strategies, the adversity in maternal health...

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  • Pharmaconutrition with Antioxidants in the Critically Ill

    Is Selenium Monotherapy the Cornerstone of this Strategy? This article explores the evolving paradigm of pharmaconutrition using antioxidant micronutrients, looking at the available evidence for antioxidant supplementation in the critically ill. In particular it discusses the protective mechanisms of action of selenite...

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  • Management of Candiduria: Grey Zones Still Exist

    Candida species cause a wide spectrum of diseases, of which the prevalence of candiduria varies considerably between nosocomial settings, being most prevalent among patients admitted to the intensive care unit (ICU). However, lacking management and treatment guidelines and the existence of dilemmas have inhibited efforts to curtail cases of...

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  • Therapeutic Hypothermia in the ICU: Indication, Sedation and Prognostication

    Mild therapeutic hypothermia (TH) applied for 24 hours in the intensive care unit (ICU) is now recommended in comatose survivors of an outof- hospital cardiac arrest (OHCA), though some uncertainty around indication, clinical management and prognostication still remains. We will probably see this exciting field of intensive care further evolve...

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  • Collective Global Action in Critical Care: An Interview with Dr. Edgar Jimenez

    As President of the World Federation of Societies of Intensive and Critical Care Medicine (WFSICCM), as well as Head of the Corporate Division of Critical Care Medicine at Orlando Health Physicians Group, Dr. Edgar Jimenez is an expert in intensive care on many levels. In this interview, Dr. Jimenez tells us about the most significant developments...

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