CAR-T Cell Therapy – What An Intensivist Should Know

• 23/11/2021

CAR-T therapy is a promising treatment for B-cell malignancies but is also associated with toxicities such as cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS). Frequent monitoring, timely recognition and prompt management in ICU are paramount to ensure good outcomes. Introduction Chimeric antigen receptor (CAR) T-cell therapy has...