Search Tag: statins

Cardiology Management

Practical hints on dealing with statin intolerance

2018 08 May

Statin intolerance is a worldwide problem concerning the inability to tolerate a dose of statin required to sufficiently reduce cardiovascular (CV) risk. However, it is worth emphasising that with the five-step approach (four-diagnostic steps + therapy), more than 90 percent of these patients might be treated with statins, according to an article published... Read more

Cardiology Management

Continued Statin Use Linked to Lower Death Risk

2017 25 Jul

A Brigham and Women's Hospital-led study published in Annals of Internal Medicine highlights the benefits of prolonged statin use. Researchers found that patients who continued receiving statins after experiencing an adverse reaction – e.g., muscle aches and pains or gastrointestinal symptoms – had lower rates of death and cardiovascular events. Among... Read more

Cardiology Management

Statins Improve Heart Structure and Function

2017 29 May

According to research presented at EuroCMR 2017, statins improve heart structure and function. The benefits of the drugs are thus above and beyond cholesterol management. Lead author Dr Nay Aung, a cardiologist and Wellcome Trust research fellow, William Harvey Research Institute, Queen Mary University of London, UK explains that while statins are... Read more

Cardiology Management

Statins in Older Adults' Primary Cardiovascular Prevention

2017 23 May

New research shows there was no benefit of a statin for all-cause mortality or coronary heart disease events when a statin was started for primary prevention in older adults with hypertension and moderately high cholesterol. The study, published in JAMA Internal Medicine, analysed data from older adults in the Lipid-Lowering Trial (LLT) component of... Read more

Cardiology Management

Statins: Muscle-Related Side Effects or Nocebo Effect?

2017 04 May

According to a new study, muscle-related symptoms are less commonly reported when patients and doctors are unaware that statin therapy is being used as compared to when these patients and doctors are aware. The findings are published in The Lancet. See Also : Low Adherence to Statins Following Heart Attack The study evaluated data on 26 side... Read more

Cardiology Management

Low Adherence to Statins Following Heart Attack

2017 19 Apr

According to a study published by JAMA Cardiology, a large proportion of patients who were prescribed high-intensity statins following hospitalisation for a heart attack did not adhere to their prescribed medication at two years after discharge. See Also : Statin Dose, Timing May Improve Heart Surgery Outcomes The study was conducted with Medicare... Read more

Cardiology Management

Study: Low Statin Use in Patients with High LDC-C Levels

2017 09 Jan

Treatment with statins is recommended for all adults 21 years or older with an elevated low-density lipoprotein cholesterol (LDL-C) level of 190 mg/dL or greater. However, a new study published in JAMA Cardiology shows low statin prescription rates even for patients in their 30s and 40s who have severe elevations in LDL-C levels. See Also... Read more

Cardiology Management

PCSK9 and HMGCR Genetic Variants Affect Cardiovascular Disease Risk

2016 06 Dec

Variants in the genes encoding HMGCR (the target of statins) and PCSK9 (the target of PCSK9 inhibitors) that lowered LDL, or "bad" cholesterol, in each gene were associated with nearly identical protective effects on the risk of cardiovascular events per unit reduction in LDL cholesterol, according to new research published in The New England Journal... Read more

Cardiology Management

Statins Combined with Stroke Prevention Drug Increase Risk of Haemorrhage

2016 22 Nov

According to a study published in the Canadian Medical Association Journal (CMAJ), two commonly used statins can increase the risk of haemorrhage when combined with dabigatran etexilate, a stroke prevention drug  used in patients with atrial fibrillation. See Also : Statins and Drug-Drug Interactions: AHA Scientific Statement A possible... Read more

Cardiology Management

Statins Before Cardiac Arrest Improve Survival Odds Afterwards

2016 14 Nov

According to a study presented at the Resuscitation Science Symposium at the American Heart Association’s Scientific Sessions 2016 , patients who have been taking statins have better chances of surviving longer after a cardiac arrest.   See Also : High-Intensity Statin Therapy Linked to Lower Risk of Death Cholesterol-lowering... Read more