Search Tag: statins

Cardiology Management

PCSK9 and HMGCR Genetic Variants Affect Cardiovascular Disease Risk

2016 06 Dec

Variants in the genes encoding HMGCR (the target of statins) and PCSK9 (the target of PCSK9 inhibitors) that lowered LDL, or "bad" cholesterol, in each gene were associated with nearly identical protective effects on the risk of cardiovascular events per unit reduction in LDL cholesterol, according to new research published in The New England Journal... Read more

Cardiology Management

Statins Combined with Stroke Prevention Drug Increase Risk of Haemorrhage

2016 22 Nov

According to a study published in the Canadian Medical Association Journal (CMAJ), two commonly used statins can increase the risk of haemorrhage when combined with dabigatran etexilate, a stroke prevention drug  used in patients with atrial fibrillation. See Also: Statins and Drug-Drug Interactions: AHA Scientific Statement A possible side effect of... Read more

Cardiology Management

Statins Before Cardiac Arrest Improve Survival Odds Afterwards

2016 14 Nov

According to a study presented at the Resuscitation Science Symposium at the American Heart Association’s Scientific Sessions 2016, patients who have been taking statins have better chances of surviving longer after a cardiac arrest.  See Also: High-Intensity Statin Therapy Linked to Lower Risk of Death Cholesterol-lowering statins are prescribed... Read more

Cardiology Management

High-Intensity Statin Therapy Linked to Lower Risk of Death

2016 12 Nov

A large, cohort study published in JAMA Cardiology demonstrates that there is an inverse association between intensity of statin therapy and mortality risk in patients with atherosclerotic cardiovascular disease (ASCVD). See Also: Statin vs Nonstatin Therapies for Lowering LDL-C Statin therapy remains the cornerstone for the prevention of ASCVD.... Read more

Cardiology Management

Statins, Aspirin Reduce Heart Attack Severity

2016 20 Sep

According to new research, medications prescribed for prevention of heart attacks such as statins and aspirin can also reduce the severity of heart attacks. The research is published in PLOS ONE and findings will be presented at the 27th Great Wall International Congress of Cardiology (GW-ICC).The study was conducted with 14,790 patients hospitalised... Read more

Cardiology Management

Statins Before Heart Surgery Reduce Complications

2016 12 Jan

A review article to be published in The Annals of Thoracic Surgery suggests the use of statins before and after coronary artery bypass grafting (CABG) surgery. The drugs are believed to reduce cardiac complications, such as atrial fibrillation, following surgery as well as the risk of death during and after surgery.Some of the key points of the review... Read more

Cardiology Management

Negative Statin Stories Impact Patients

2015 06 Dec

According to a study published in the European Heart Journal, negative news stories about statins result in some people choosing to discontinue their statin treatment which in turn increases their risk of heart attacks and dying from heart disease. The research was conducted by researchers in Denmark and included 674,900 people aged 40 and older who... Read more

Cardiology Management

Poor Levels of Availability, Affordability, Use of Vital Heart Medicines

2015 27 Oct

According to research published in The Lancet, the use of vital life-saving generic medicines for the prevention of heart disease is poor worldwide. In low-income and middle-income countries, these medicines are either not easily available or if they are, they are often unaffordable. In rich countries, availability and affordability is not usually an... Read more

Cardiology Management

Elderly have Highest Rate of Statin Use

2015 24 Aug

According to new research published by JAMA Internal Medicine, the use of statins for primary prevention in patients without vascular disease between 1999 and 2012 significantly increased among the elderly despite the fact that there is no evidence to recommend the use of these drugs in this particular patient segment. The study was conducted by Michael... Read more

Cardiology Management

Statins: A Double-Edged Sword

2015 17 Aug

A new study published in the American Journal of Physiology - Cell Physiology talks about how statins are beneficial in some cases but highlights the importance of weighing individual risk before using statins as preventive therapy. Statins have proven to be quite effective in reducing atherosclerosis-related events and some researchers have gone so... Read more


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