Search Tag: organ dysfunction

ICU Management

Time to Move From SOFA 1.0 to 2.0?

2023 23 Jan

The Sequential Organ Failure Assessment (SOFA) score was developed in 1994, more than 25 years ago. The primary purpose of the score was to provide clinicians with a method that could help them assess and monitor organ dysfunction in critically ill patients. SOFA score became one of the most widely used scoring systems in intensive care. However, many... Read more

Sepsis

Intravenous Vitamin C in ICU Patients with Sepsis

2022 21 Jun

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis contributes to between a third and a half of deaths in hospitals. It is responsible for nearly 11 million deaths worldwide each year. Treatment of sepsis typically includes antimicrobial therapy, source control, and organ support. It is believed... Read more

ICU Management

COVID-19: Vascular Endothelium and Organ Dysfunction

2020 25 Jun

The effect of COVID-19 on endothelial cells (ECs) is emerging to be an important area of research for the effective management of severely ill patients. In the early phase of the pandemic, there was little attention paid to this effect and how it mediates organ dysfunction and even failure in extreme cases.     The endothelium has several critical... Read more

ICU Management

In-line Filtration Reduces Organ Dysfunction, Inflammation

2019 01 Dec

Patients admitted to the intensive care unit are administered drugs, fluid, and blood products intravenously. In the vast majority of these patients, there are no untoward effects of the intravenous infusion. However, young children and neonates who are ill are usually administered intravenous infusions with the use of in-line filters. The philosophy... Read more

ICU Management

Cardiac arrest-related organ failure: impact on long-term outcome

2019 06 Mar

Organ dysfunction is common after cardiac arrest and associated with worse short-term outcome. New research shows that extracerebral organ failure, measured as the 24 hour-EC-SOFA score, is also an important contributor to both long-term outcome and increased healthcare-associated costs in cardiac arrest patients.   For this retrospective... Read more

ICU Management

Old Blood as Good as Fresh

2015 17 Mar

A large clinical trial provides reassuring evidence about the safety of blood routinely transfused to critically ill patients, with data showing that blood stored for three weeks is just as good as fresh blood. The findings are published online in The New England Journal of Medicine . A team of researchers from 64 Canadian and European centres conducted... Read more