Search Tag: oestrogen

ICU Management

COVID-19: Molecular Mechanisms of Gender Differences

2020 30 Jul

The COVID-19 pandemic has resulted in hundreds of thousands of deaths around the globe. An important thing to note is that more men have died from COVID-19 than women. A European study shows that men had a slightly higher incidence of COVID-19 with no respiratory distress compared to women. Still, more males with COVID-19 developed severe respiratory... Read more

Executive Health Management

The Sex and Gender Influence on Hypertension

2019 02 Oct

Despite underlying physiological differences and a different set of risk factors, diagnosis, management, and treatment strategies for hypertension do not account for sex and gender variances. Evidence-based guidelines for hypertension treatment from clinical trials are similar between males and females; however, most of these trials do not... Read more

Executive Health Management

Sex & Gender Impacts in Cardiovascular Disease: A “Typical” Presentation of Cardiovascular Disease?

2019 26 Aug

Summary: Differences in sex and gender may account for gaps in treatment and prevention of cardiovascular disease, but at the same time, it also gives the opportunity for personalised sex and gender-specific medicine.   Typical presentations in medicine are defined in ways that health care professionals can draw on past experiences and education... Read more

Cardiology Management

Pesticide Exposure Increases Risk of Heart Disease

2015 09 Apr

A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism suggests that pesticide exposure, not obesity alone, can contribute to increased cardiovascular disease risk and inflammation in premenopausal women. The use of polychlorinated pesticides such as DDT remains widespread in the environment and food supply.... Read more

Cardiology Management

High Testosterone Levels Increase Risk of Heart Disease

2015 09 Mar

A new study shows that sex hormones testosterone and oestrogen alter cardiovascular risk factors in a way that increases a man's risk of heart disease. The results of this study will be presented at the 97th Annual Meeting of the Endocrine Society in San Diego. Doctors have long suspected that testosterone may promote cardiovascular disease and... Read more

Pharmacy Management

Hormone Replacement Therapy Increases Risk of Ovarian Cancer

2015 20 Feb

According to an extensive meta-analysis from the Collaborative Group on Epidemiological Studies of Ovarian Cancer, hormone replacement therapy (HRT) was associated with an increased risk for ovarian cancer in postmenopausal women. To date, studies that have examined a link between HRT and ovarian cancer risk have been small and/or retrospective... Read more

Lab Management

Innovative Prognostic Test for E2F4 in Breast Cancer

2015 12 Jan

Researchers at Dartmouth Hitchcock’s Norris Cotton Cancer Center (NCCC) have identified a gene signature in E2F4 that is predictive of oestrogen receptor positive (ER+) breast cancer. With the aim to design an accurate and simple genomic test to measure the activity levels of the regulators associated with E2F4, the investigators looked to the aberrant... Read more