Search Tag: obese

ICU Management

Vancomycin pharmacokinetics in critically ill obese patients

2019 23 Jan

Limited data are available assessing vancomycin concentrations in obese critically ill patients. Several physiologic changes in obesity affect antimicrobial pharmacokinetics. For example, the volume of distribution in obese patients is greater due to increased lean body mass and adipose tissue. Drug clearance may also be further enhanced due to... Read more