Search Tag: mortality

Sepsis

Association-of-active-renin-content-with-mortality

2023 22 Nov

Sepsis affects 1.7 million patients annually, with a mortality rate of 10–50%. Current biomarkers like WBC count, lactate, and blood cultures have variable impacts on prognosis. Recent evidence suggests that circulating renin is proposed as a more predictive biomarker for septic shock outcomes than lactate.  The Vitamin C, Thiamine, and Steroids...Read more

Sepsis

Data-to-track-incidence-mortality-for-sars-cov-2-associated-sepsis

2023 03 Oct

Sepsis is a life-threatening condition resulting from a dysregulated response to infection, historically associated with bacterial infections. However, viral infections are increasingly recognised as significant contributors to sepsis, especially with events like the SARS-CoV-2 pandemic and surges of respiratory viruses like RSV and influenza. Despite...Read more

ICU Management

Time-definition-of-reintubation

2023 03 Oct

Mechanical ventilation is crucial for supporting critically ill patients, and a timely extubation strategy is essential for improved patient outcomes. Despite standard weaning procedures, a significant percentage of patients (3-20%) require reintubation. Post-extubation respiratory failure can cause respiratory fatigue, requiring additional mechanical...Read more

Cardiology Management

Smartphones-predict-mortality-risk

2022 25 Oct

Physical activity is associated with mortality risk. Several studies have shown that people who engage in more moderate-to-vigorous activity and are less sedentary have lower mortality rates. These findings have been further confirmed in meta-analyses in which activity sensors record total activity and statistical models predict mortality risk using...Read more

Sepsis

Icu-vs-high-dependency-care-unit-for-septic-shock

2022 26 Jul

Sepsis is a life-threatening disease with high mortality. More than 10,000 people die from sepsis every year in Japan. Septic shock is when sepsis is associated with circulatory and cellular metabolic abnormalities. International guidelines recommend the use of antimicrobial therapy and source control with drainage or surgery, intensive care with fluid...Read more

ICU Management

Clinical-organisational-factors-and-covid-19-mortality

2022 31 May

Coronavirus disease 2019 (COVID-19) is one of the most significant challenges faced by critical care workers worldwide. During the COVID-19 pandemic, an unprecedented number of patients with COVID-19 associated pneumonia were admitted to the ICU. As a result, most healthcare facilities faced capacity issues and had to designate clinical areas to accommodate...Read more

Cardiology Management

Heart-attack-mortality-variation-across-high-income-countries

2022 10 May

According to new findings published in The BMJ, U.S. has the highest heart attack mortality rate across six high income countries. The country may have the latest tech and low readmission rates, but its mortality rate is one of the highest in the world.  Interestingly, the study has found substantial differences in care for heart attack patients...Read more

ICU Management

Clinical-subtypes-in-sepsis-survivors

2022 27 Apr

The risk of late mortality in sepsis survivors can persist for years with high readmission rates and poor quality of life. However, due to an incomplete understanding of the relevant causal mechanisms of post-sepsis syndrome, there has been limited success in implementing preventive interventions.  The French and European Outcome Registry in Intensive...Read more

ICU Management

Icu-capacity-transfers-and-mortality

2022 12 Apr

Transfers from one ICU to another ICU are associated with an increased length of stay in the ICU and the hospital. Inter-hospital ICU transfers occur for three main reasons: clinical transfers, capacity transfers and repatriations.  A study was conducted to show that different ICU transfers differ in risk-adjusted mortality rate. The primary endpoint...Read more

ICU Management

Therapeutic-hyperthermia-and-survival-in-critically-ill-afebrile-sepsis-patients

2022 15 Feb

A major feature of infection is fever. However, less than half of critically ill patients with sepsis have a fever at the time of diagnosis. Afebrile patients with sepsis have nearly twice the mortality and are more likely to develop secondary infections than patients with fever. Fever is thus an adaptive response to the infection and is critical for...Read more

ICU Management

Ea21-middle-aged-men-more-likely-to-die-after-surgery-than-middle-aged-women

2021 19 Dec

New research presented at Euroanaesthesia 2021 shows that middle-aged men are nearly 50% more likely to die after surgery than middle-aged women.   Previous studies also report sex differences in the risk of complications after surgery, but the results have been mixed. One study showed that men were at higher risk of complications and death after...Read more

ICU Management

Outcome-after-intubation-for-septic-shock

2021 09 Nov

Acute respiratory failure in septic patients is associated with higher in-hospital mortality. Early management and treatment with antibiotics, fluids, vasopressors, and source control, can reduce morbidity and mortality. Sepsis-related acute respiratory failure is also frequent and may require non-invasive or invasive ventilator support.   While...Read more

ICU Management

Impact-of-treatment-variability-on-ards-mortality

2021 02 Nov

Acute Respiratory Distress Syndrome (ARDS) is a potentially fatal condition characterised by acute hypoxaemia, and bilateral radiographic infiltrates and a mortality of 36 to 47%. Interventions like lung protective ventilation (LPV) and prone positioning have been shown to improve survival but remain underused. Other treatment methods such as neuromuscular...Read more

ICU Management

Mortality-differences-in-critically-ill-elderly-during-covid-19

2021 29 Sep

A study was conducted to assess the outcome of elderly intensive care unit patients who were treated during the spring and autumn surges of COVID-19 in Europe. The COVIP study included patients aged 70 years and older who were admitted with COVID-19 from March to December 2020. A total of 2625 patients – 1327 from the first surge of the pandemic...Read more

ICU Management

Trends-in-sepsis-related-mortality-in-the-u-s

2021 27 Jul

Sepsis is a life-threatening organ dysfunction. It is the leading cause of death in the U.S. It is also one of the most expensive conditions to treat. However, the burden of sepsis-related mortality in the U.S. in recent years is not well-characterised. Previous studies utilise hospital databases and electronic health records to determine trends, but...Read more

ICU Management

Association-of-volume-of-sepsis-cases-and-mortality

2021 06 Jul

Sepsis is a leading cause of death worldwide and is also associated with a high burden of patient mortality.  This burden is expected to increase as populations age. Patients with sepsis typically require high-cost interventions in ICUs. Even with urgent treatment, the probability of death still remains high. However, ICUs that have more experience...Read more

ICU Management

Safety-of-enhanced-thromboprophylaxis-strategies-for-covid-19-patients

2021 04 May

COVID-19 is associated with a high incidence of thrombotic complications. The burden of thrombin complications, in particular, pulmonary embolism, remains high in patients with COVID-19, especially those requiring admission to the ICU. Data suggest an incidence of thromboembolic events between 27 to 57% in COVID-19 patients despite standard thromboprophylaxis....Read more

ICU Management

Antibiotic-delay-intervals-mortality-among-patients-with-suspected-sepsis

2021 27 Apr

Timely delivery of antibiotics is a major cornerstone of sepsis therapy. Clinical evidence suggests that every one-hour delay in antibiotics after emergency department (ED) triage or the onset of organ dysfunction or shock could result in a 3-7% increase in the odds of a poor outcome. The Surviving Sepsis Campaign (SSC) guidelines recommend antibiotic...Read more

Executive Health Management

Covid-19-outcomes-in-healthcare-staff

2021 25 Apr

A new study explores the data on COVID-19 infections and deaths among healthcare workers around the world and outlines some implications for policy and practice.   You might also like: Almost 1 in 3 COVID-19 patients admitted to ICU in U.S. hospitals died, although the mortality rate decreased over the course of the pandemic, a new...Read more

Executive Health Management

Covid-19-vs-influenza-comparative-study

2021 20 Mar

New research compares the epidemiology and clinical characteristics of COVID-19 patients against those of influenza patients to find if hospitalis ations, morbidity and mortality differ for two diseases.   You might also like: WHO has launched a free online course dedicated to the rehabilitation of COVID-19 patients. Learn more...Read more

ICU Management

Ecmo-mortality-and-ards

2021 01 Feb

An in-depth analysis was conducted in Germany to evaluate whether mortailty in Germany in Extracorporeal life support (ECLS) therapy differed from previously reported literature.  Extracorporeal life support (ECLS) is a critical component of intensive care therapy. There are various conditions that require the use of ECLS. The term ECLS encompasses...Read more

ICU Management

Tocilizumab-and-covid-19-pneumonia

2020 26 Oct

Tocilizumab is a humanised monoclonal antibody that binds human interleukin 6 (IL-6) receptors. It is generally used in inflammatory arthritis, giant cell arteritis and cytokine release syndrome after chimeric antigen receptor T-cell therapy.   Tocilizumab has come under close scrutiny during the COVID-19 pandemic. Early observations from China...Read more

Health Management

Volume-20-issue-3-2020

2020 11 May

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ICU Management

Optimal-approach-to-fluid-resuscitation-for-patients-in-shock

2020 03 Feb

Initial fluid resuscitation practices for patients with haemodynamic shock remain controversial. There is significant variability in these practices, and the impact of this is still poorly understood. Overall, non-patient-centred resuscitation practices, conflicting treatments, variability, and failure to meet targets for initial resuscitation are...Read more

Cardiology Management

Life-expectancy-and-mortality-rates-in-the-us

2019 01 Dec

Examining life expectancy in the United States over nearly 60 years and identifying factors that contributed to recent increases in mortality were the focus of a new report. The report, "Life Expectancy and Mortality Rates in the United States, 1959-2017," is one of the most comprehensive 50-state analyses of mortality in the US. Researchers...Read more

ICU Management

Using-biomarkers-for-mortality-prediction-in-patients-with-sepsis

2019 23 Nov

Sepsis has always carried high mortality. Even today, with all the latest technology and newer antibiotics, sepsis continues to be a major risk factor for death. It is important to understand that the earlier sepsis is diagnosed and treated, the better the prognosis. Each year, nearly 6 million people die of sepsis in the US.  Because of its aggressive...Read more

ICU Management

Timing-of-death-among-patients-with-septic-shock

2019 14 Nov

Over the last few years, many advances have been made in the critical care of patients with septic shock. Both diagnosis and treatment strategies have improved. However, the mortality rates of patients with septic shock have a bimodal distribution; some patients die within a few days from it, while others die a few weeks later from other comorbidities. ...Read more

ICU Management

Risk-factors-for-frailty-and-death-in-the-icu

2019 07 Nov

The population continues to age, and life expectancy continues to increase. While most elderly patients can be managed in the general ward, a certain percentage will need ICU admission. The number of elderly people admitted to the critical care unit has been increasing consistently. However, age alone is not a key factor for admission to the ICU....Read more

Cardiology Management

Can-dog-ownership-improve-survival-in-patients-with-cardiovascular-disease

2019 12 Oct

Dog ownership may be associated with longer life and better cardiovascular outcomes, especially for heart attack and stroke survivors who live alone, according to a new study and a separate meta-analysis published in Circulation: Cardiovascular Quality and Outcomes, a journal of the American Heart Association. "The findings in these two well-done...Read more

Executive Health Management

The-sex-and-gender-influence-on-hypertension

2019 02 Oct

Despite underlying physiological differences and a different set of risk factors, diagnosis, management, and treatment strategies for hypertension do not account for sex and gender variances. Evidence-based guidelines for hypertension treatment from clinical trials are similar between males and females; however, most of these trials do not...Read more