Search Tag: hypothermia
2024 28 Oct
Temperature control in managing post-anoxic brain injury remains debated. The Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest (TTM-2) trial showed no improvement in mortality or functional outcomes with therapeutic hypothermia at 33 °C in unconscious out-of-hospital cardiac arrest (OHCA) patients, compared to early fever avoidance...Read more
2022 23 Nov
Out-of-hospital cardiac arrest (OHCA) typically has a poor prognosis. Less than 50% of patients admitted to ICU survive to hospital discharge. Animal models suggest that therapeutic hypothermia is neuroprotective and decreases neuronal injury. Targeted temperature management (TTM 33–36 °C) is part of international guidelines when managing post-OHCA...Read more
2021 22 Jun
Since 2005, the guidelines for the care of unconscious cardiac arrest patients have been to cool the body temperature down to 33 degrees Celsius. However, findings from a large, randomised clinical trial led by Lund University and Region Skåne in Sweden show that this treatment does not improve survival. "These results will affect the current...Read more
2019 03 Oct
In one of the sessions at #LIVES2019 in Berlin, Prof. Frank Van Haren of Canberra Hospital, Australia, presented findings from the Randomised Evaluation of Active Control of Temperature versus Ordinary Temperature Management (REACTOR) trial. The question which this study aimed to answer was whether there is a reason why fever should be actively...Read more
2018 16 Mar
Hypothermia (HT) is a cornerstone of neuroprotective strategies and has been used in critical care for acutely brain injured adult patients for many years. This review aims to discuss the clinical evidence supporting the use of HT in neurocritical care patients beyond care after cardiac arrest (CA), such as traumatic brain injury (TBI), acute ischaemic...Read more
2017 25 Aug
NICE has developed a medtech innovation briefing (MIB) on the Arctic Sun® 5000 Temperature management System. The Arctic Sun® 5000 Temperature management system is a non-invasive system for controlling and monitoring body temperature within the range of 32°C to 38.5°C. It is intended for use in adults who are comatose after sudden cardiac...Read more
2016 27 Sep
Managing patients with accidental hypothermia with and without cardiac arrest is covered in a recently published state-of-the-art review, endorsed by the International Commission for Mountain Emergency Medicine. Extracorporeal life support is the “treatment of choice” in patients with unstable circulation or cardiac arrest. Peter Paal and colleagues...Read more