Search Tag: hydroxychloroquine
Twenty Lessons from 2020: With a Focus on the ICU Perspective
2021 22 Feb
2020 has been an unusual year. As we begin 2021, it is important for intensivists to look back over what has happened and see whether lessons can be learned from our combined experiences . T he year 2020 has been unusual in so many ways and as we start a new year, it is interesting and important as intensivists to look back and reflect on what... Read more
Is the Severe COVID-19 Over in Europe?
2020 11 Aug
Is the worst over? Have patients most at risk already been affected and died? Or has the SAR-CoV-2 virus mutated to a less severe form? Where exactly do we stand with COVID-19? U ndoubtedly, the COVID-19 pandemic has been a terrible experience - worse than expected for many worldwide. As we follow the COVID-19 situation, there is a tendency... Read more
COVID-19: Hydroxychloroquine With or Without Azithromycin
2020 28 Jul
Hydroxychloroquine and azithromycin have been used to treat COVID-19 patients, but there is very little evidence with respect to the safety and efficacy of this treatment strategy. Hydroxychloroquine has antiviral effects, and combined with azithromycin, it was believed that it could decrease SARS-CoV-2 viral load (based on results from a small,... Read more
FDA & MHRA Revoke COVID-19 Authorisations for Hydroxychloroquine
2020 16 Jun
The U.S. Food and Drug Administration has revoked its emergency use authorisation for chloroquine and hydroxychloroquine as treatments for COVID-19. The U.K. Medicines and Healthcare products Regulatory Agency has followed suit, but Brazil criticised the decision and expanded the drugs’ use. You might also like: Warnings about Potential... Read more
Potential COVID-19 Treatments: Some In, Some Out
2020 27 May
The UK health ministry has announced that the antiviral drug remdesivir would be made available to selected COVID-19 patients while the World Health Organization (WHO) is putting the hydroxychloroquine/chloroquine arm within the COVID-19 Solidarity Trial on hold. You may also like : From Hydroxychloroquine and Remdesivir to Plasma Administration... Read more
From Hydroxychloroquine and Remdesivir to Plasma Administration
2020 19 May
Clinicians are faced with a serious disease with no effective therapy. Several options are being considered to treat COVID-19, but how promising are these drugs? A number of colleagues and friends from outside the hospital have asked me whether they should take hydroxychloroquine for their COVID-19. A friend asked me whether he should... Read more
Association Between Hydroxychloroquine or Azithromycin and In-Hospital Mortality
2020 18 May
As of May 2020, at least a quarter of a million people worldwide have died from COVID-19. Over the past four months, many treatments have been suggested for this disease but none have worked so far. Hydroxychloroquine has been too much in the news, in particular. Laboratory evidence has indicated that the use of hydroxychloroquine can inhibit the... Read more
Hydroxychloroquine and QT Prolongation
2020 06 May
As the healthcare community attempts to deal with the coronavirus disease (COVID-19), there is an intense effort to develop an effective treatment strategy. While research on the development of a vaccine continues, clinicians have been forced to use treatments that lack robust clinical evidence. With many patients succumbing to acute respiratory distress... Read more
Warnings about Potential Treatments for COVID-19
2020 09 Apr
An early-released review warns about potentially serious adverse events for chloroquine, hydroxychloroquine and azithromycin when used to treat and prevent COVID-19 . It comes only days after the U.S. Centers for Disease Control and Prevention (CDC) had removed guidelines for using hydroxychloroquine as a potential treatment. ... Read more