Search Tag: cardioprotective effects

Cardiology Management

Cardioprotective role of metformin

2019 25 Apr

Left ventricular hypertrophy (LVH) is found in nearly one-third of patients with coronary artery disease (CAD). LVH is an independent predictor of mortality and is a powerful prognostic factor in CAD. Regression of LVH can reduce the incidence of major cardiovascular events. Insulin resistance (IR) may play a role in the development of LVH.... Read more

Cardiology Management

PCSK9 and HMGCR Genetic Variants Affect Cardiovascular Disease Risk

2016 06 Dec

Variants in the genes encoding HMGCR (the target of statins) and PCSK9 (the target of PCSK9 inhibitors) that lowered LDL, or "bad" cholesterol, in each gene were associated with nearly identical protective effects on the risk of cardiovascular events per unit reduction in LDL cholesterol, according to new research published in The New England Journal... Read more