Search Tag: cardio-oncology

Cardiovascular Adverse Events After Treatment With BRAF and MEK Inhibitors

2019 19 Aug

Melanoma accounts for nearly 55500 cancer deaths annually worldwide. Most mutations in melanoma occur at the level of BRAF with an upregulation of the MAPK pathway. BRAF mutations prompted the development of BRAF inhibitors which cause resistance through a signalling cascade mediated by MEK. This, in turn, led to the development of MEK inhibitor... Read more

Cardio-oncology: managing non-heart failure toxicities

2019 27 Feb

New drugs and therapies have led to improvement in cancer patients’ survival; however, cardiovascular toxicity is a reality that impacts on the quality of life of these patients. Cardio-oncology, the multidisciplinary cardiovascular care of cancer patients, has been proposed as a new approach to improve prevention, early identification and management... Read more

Cardiology World Conference 2019

2019 24 Oct

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Important challenges to cardio-oncology

2018 11 Jul

Is it cardio-oncology or onco-cardiology? More than the issue of adoption of an appropriate name for this subspeciality, this new and promising field is beset with some rectifiable challenges, according to an article published in the Journal of the American College of Cardiology. The article traces the origin of this subspeciality, noting that... Read more

Developing 'Best Practice' in Cardio-oncology

2017 20 Jun

Cardiovascular toxicity has become a challenging issue during cancer therapy. A survey of oncologists in France reveals that respondents commonly (>90%) prescribe therapies that are associated with cardiotoxicity. Interestingly, the survey shows that the assessment and management of the cardiovascular status of cancer patients is often inconsistent... Read more

Cardio-Oncology: A Developing Specialty for Comprehensive Cardiac Care

2016 05 Jan

Over the past several decades there have been significant and important improvements in the care of patients diagnosed with cancer, and there are currently an estimated 14.5 million survivors of cancer in the U.S., or approximately 4.5% of the total population (DeSantis et al. 2014). One unintended consequence of this success is a growing population... Read more

Volume 15 - Issue 4, 2015

2015 30 Dec

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Can Cancer Damage the Heart?

2015 06 Dec

New research presented at EuroEcho-Imaging 2015 raises the possibility that cancer may damage heart muscle irrespective of exposure to cancer drug therapies.  The research from UK's first dedicated cardio-oncology clinic found that both treated and untreated cancer patients had impaired heart function.  Dr Rajdeep S. Khattar, last author of the abstract... Read more

Cardio-oncology Services can Improve Patient Care

2015 28 Jun

According to a survey published in the American Journal of Cardiology , lack of hospital training programs, no formal training or services in cardio-oncology, lack of national guidelines and funding are significant barriers to the establishment of cardio-oncology services. Studies indicate that many cancers and heart disease are linked through... Read more