Search Tag: antimicrobial stewardship

Sepsis in Critical Care: Effective Antimicrobial Strategies in ICU

2022 16 Mar

ICU sepsis is associated with a mortality rate >25%, with nosocomial infection most lethal, and community acquired infection more common. Optimal management requires identification of the site of infection (lung, abdomen and blood stream most commonly), a focus on the likely pathogens based on risk factors for resistance, and provision of timely and... Read more

ICU Management

2018 19 Jun

Medical decision-making about antibiotic use in critically ill patients is challenging and complex. The need for antibiotic stewardship requires judicious prescription and choice of antimicrobials, as the need for effective therapy has to be put in balance with the need to limit undue selection pressure, and all this must be done in a context of... Read more

Volume 17 - Issue 1, 2017

2017 16 Mar

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Antimicrobial Use for IAI: New Guidance

2016 11 Oct

Guidance on empiric antimicrobial therapy for patents with intra-abdominal infections (IAI) has been drawn up by a task force from 79 countries, the  Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections- AGORA project. The experts recommend timely effective source control with appropriate antimicrobial therapy... Read more

Implementing Antimicrobial-Stewardship Programme in ICUs

2016 30 Aug

Antimicrobial resistance is a major healthcare challenge, especially in the intensive care unit (ICU) as ICU patients are more susceptible to healthcare-associated infections (HAIs). It is also a severe problem in ICus because patients are critically ill and immuncomprised and have undergone major surgical procedures. Most ICUs do not have effective... Read more

Combating Infections in the ICU: Dual Approach

2016 28 Mar

A combination of strict antimicrobial stewardship and comprehensive infection control measures led to a 10-fold reduction in multi-drug resistant (MDR) A. Baumannii that had become endemic in a Korean intensive care unit (ICU). The initative is described in a recent paper in the Korean Journal of Internal Medicine . Shinhye Cheon, Division... Read more

Optimising Antibiotics and Antimicrobial Stewardship in the ICU

2016 05 Jan

Antibiotic dosing regimens for critically ill patients require constant vigilance, due to extreme shifts on organ function that can impact on drug exposure. In a  recent article in Medicina Intensiva  Australian researchers Menino Cotta, Jason Roberts and Jeffrey Lipman recommend therapeutic drug monitoring and individualising and tailoring dose for... Read more