Search Tag: antimicrobial resistance

Sepsis in Critical Care

2022 16 Mar

Sepsis is a leading cause of morbidity and mortality in the intensive care unit. Nearly  14 million adults and 2.5 million children  survive sepsis each year worldwide. In addition, sepsis survivors are known to experience poor long-term outcomes and often develop functional limitations thereafter. It is thus evident that the long-term impact... Read more

Sepsis in Critical Care: Effective Antimicrobial Strategies in ICU

2022 16 Mar

ICU sepsis is associated with a mortality rate >25%, with nosocomial infection most lethal, and community acquired infection more common. Optimal management requires identification of the site of infection (lung, abdomen and blood stream most commonly), a focus on the likely pathogens based on risk factors for resistance, and provision of timely and... Read more

PCT-guided Antibiotic Stewardship in COVID-19 Patients

2020 14 Sep

Professor Michael Mansour is a physician-scientist with a research concentration in immune responses against invading pathogens. He attends on the Clinical Transplant Infectious Diseases and Immunocompromised Host Service at the Massachusetts General Hospital - Division of Infectious Diseases, where he cares for solid and stem cell transplant recipients... Read more

#LIVES2019: Findings from the DIANA Study

2019 01 Oct

Liesbet De Bus of Ghent University Hospital, Belgium, presented the findings of the DetermInants of Antimicrobial use aNd de-escalAtion (DIANA) study @ESICM #LIVES2019 in Berlin.  Dr. De Bus started off by explaining the concept of de-escalation and how it is all about finding a balance between early adequate antimicrobial therapy on the one... Read more

Trends in epidemiology and antimicrobial resistance in intensive care units

2019 14 Mar

The intensive care unit has a unique environment, mainly because it treats severe and critically ill patients who require special care. Critical care patients often require high-risk surgeries, and there is also a frequent need for invasive devices such as central or peripheral venous catheters, urinary catheters or tracheal tubes, among others. This... Read more

Results of antimicrobial stewardship programme implementation in multidisciplinary hospital

2018 01 Jun

The interventional single-centre with historical control study was conducted in a 600-bed multidisciplinary hospital to evaluate 4 years’ results of an antimicrobial stewardship programme. We found a significant reduction in average duration of courses of antimicrobial therapy, length of stay of patients with infection in ICU, mortality in patients... Read more

Antimicrobial Use for IAI: New Guidance

2016 11 Oct

Guidance on empiric antimicrobial therapy for patents with intra-abdominal infections (IAI) has been drawn up by a task force from 79 countries, the  Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections- AGORA project. The experts recommend timely effective source control with appropriate antimicrobial therapy... Read more

Hospital Superbug Breakthrough

2015 14 Jun

A cutting-edge medical therapy has been developed by researchers at Queen’s University, Belfast that could protect patients against a lethal superbug. The treatment uses a molecule called an inhibitor and prevents the superbug Klebsiella pneumonia from blocking the body’s natural defences. Klebsiella has a mortality rate of 25 to 60 percent... Read more

EAHP: 2015 Year of Action on Antimicrobial Resistance

2015 12 Jan

The European Association of Hospital Pharmacists (EAHP) has issued a call to policy-makers in the European Union to make 2015 a year of action with respect to the antimicrobial resistance challenge. The new policy statement published by 34 national member associations reminds policy makers of the opportunities available to them as well as highlights... Read more