Search Tag: antimicrobial resistance
Sepsis in Critical Care
2022 16 Mar
Sepsis is a leading cause of morbidity and mortality in the intensive care unit. Nearly 14 million adults and 2.5 million children survive sepsis each year worldwide. In addition, sepsis survivors are known to experience poor long-term outcomes and often develop functional limitations thereafter. It is thus evident that the long-term impact... Read more
Sepsis in Critical Care: Effective Antimicrobial Strategies in ICU
2022 16 Mar
ICU sepsis is associated with a mortality rate >25%, with nosocomial infection most lethal, and community acquired infection more common. Optimal management requires identification of the site of infection (lung, abdomen and blood stream most commonly), a focus on the likely pathogens based on risk factors for resistance, and provision of timely and... Read more
PCT-guided Antibiotic Stewardship in COVID-19 Patients
2020 14 Sep
Professor Michael Mansour is a physician-scientist with a research concentration in immune responses against invading pathogens. He attends on the Clinical Transplant Infectious Diseases and Immunocompromised Host Service at the Massachusetts General Hospital - Division of Infectious Diseases, where he cares for solid and stem cell transplant recipients... Read more
#LIVES2019: Findings from the DIANA Study
2019 01 Oct
Liesbet De Bus of Ghent University Hospital, Belgium, presented the findings of the DetermInants of Antimicrobial use aNd de-escalAtion (DIANA) study @ESICM #LIVES2019 in Berlin. Dr. De Bus started off by explaining the concept of de-escalation and how it is all about finding a balance between early adequate antimicrobial therapy on the one... Read more
Trends in epidemiology and antimicrobial resistance in intensive care units
2019 14 Mar
The intensive care unit has a unique environment, mainly because it treats severe and critically ill patients who require special care. Critical care patients often require high-risk surgeries, and there is also a frequent need for invasive devices such as central or peripheral venous catheters, urinary catheters or tracheal tubes, among others. This... Read more
Results of antimicrobial stewardship programme implementation in multidisciplinary hospital
2018 01 Jun
The interventional single-centre with historical control study was conducted in a 600-bed multidisciplinary hospital to evaluate 4 years’ results of an antimicrobial stewardship programme. We found a significant reduction in average duration of courses of antimicrobial therapy, length of stay of patients with infection in ICU, mortality in patients... Read more
Antimicrobial Use for IAI: New Guidance
2016 11 Oct
Guidance on empiric antimicrobial therapy for patents with intra-abdominal infections (IAI) has been drawn up by a task force from 79 countries, the Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections- AGORA project. The experts recommend timely effective source control with appropriate antimicrobial therapy... Read more
Hospital Superbug Breakthrough
2015 14 Jun
A cutting-edge medical therapy has been developed by researchers at Queen’s University, Belfast that could protect patients against a lethal superbug. The treatment uses a molecule called an inhibitor and prevents the superbug Klebsiella pneumonia from blocking the body’s natural defences. Klebsiella has a mortality rate of 25 to 60 percent... Read more
EAHP: 2015 Year of Action on Antimicrobial Resistance
2015 12 Jan
The European Association of Hospital Pharmacists (EAHP) has issued a call to policy-makers in the European Union to make 2015 a year of action with respect to the antimicrobial resistance challenge. The new policy statement published by 34 national member associations reminds policy makers of the opportunities available to them as well as highlights... Read more