Search Tag: antibiotic therapy


Prehospital Bundle of Care Associated With Mortality Decrease in Septic Shock

2022 11 Oct

Over 50 million people worldwide suffer from sepsis every year. Sepsis causes nearly 11 million deaths and is responsible for one-third to half of all in-hospital deaths. The mortality rate for sepsis ranges from 10 to 20%. For septic shock, the most serious form of sepsis, the mortality rate can range from 50 to 60%.  Guidelines recommend early... Read more

ICU Management

Long vs Short Duration Antibiotic Therapy for VAP

2022 24 May

Ventilator-associated pneumonia (VAP) is a major cause of morbidity and mortality in the ICU. It accounts for nearly 25% of infections in ICU patients. While there are guidelines to treat VAP, uncertainties remain when treating VAP due to Pseudomonas aeruginosa (PA-VAP), and the optimal duration of antibiotic therapy continues to be debated. In addition,... Read more

ICU Management

Timing of Antibiotic Therapy in the Intensive Care Unit

2021 19 Oct

Severe infections are common among patients in the ICU. According to findings from the Extended Study on Prevalence of Infection in Intensive Care III (EPIC III), 54% of the study patients had at least one suspected or proven infection on the study day, and 24% of these patients had more than one suspected or proven infection.   These infections... Read more

ICU Management

Sepsis: early lactate measurements make a difference

2018 29 May

Sepsis has become a leading cause of in-hospital death and new research findings may help explain why this is so. A significant number of patients with suspected sepsis do not have their lactates measured within the recommended timeframe and, as a result, they experience delayed antibiotic therapy and IV fluid administration, as well as increased... Read more

ICU Management

HHFT pioneers use of diagnostic tools for earlier optimisation for sepsis patients

2018 08 May

… Antimicrobial Susceptibility Testing (AST) times reduced from days to hours….   Hampshire Hospitals NHS Foundation Trust (HHFT) is pioneering the use of the Accelerate Pheno TM system from Accelerate Diagnostics, Inc., (Accelerate Diagnostics) a leading in vitro diagnostics company, to speed up and improve the diagnostic outcome of antibiotic... Read more