Search Tag: antibiotic resistance
COVID-19 and Antimicrobial Stewardship
2020 19 Oct
COVID-19 is a new disease. On initial presentation, clinicians can find it difficult to differentiate between coronavirus disease and bacterial community-acquired pneumonia. COVID-19 patients often develop a hyperinflammatory phase during the disease process, which could again be difficult to distinguish from a secondary bacterial infection. That is... Read more
Biomarker-Guided Antibiotic Stewardship in Suspected Ventilator-Associated Pneumonia
2019 15 Dec
Ventilator-associated pneumonia carries enormous morbidity and mortality, including prolonging hospital stay and increasing the cost of healthcare. In most cases, ventilator-associated pneumonia occurs without any specific signs or symptoms. Making an accurate diagnosis is often difficult. Unlike the past, the administration of empirical antibiotics... Read more
Antibiotic timing and administration in the ED
2019 01 May
Antibiotics are often prescribed in the emergency department (ED) to patients with suspected infection before any definitive diagnosis can be made. However, amidst increasing antibiotic resistance, their use should be limited to those at high risk of infection or further clinical deterioration. Current tools to aid clinical decision-making include... Read more
Results of the ABATE infection trial
2019 14 Mar
According to results of the ABATE infection trial, daily bathing with an antiseptic soap, plus nasal ointment for patients with prior antibiotic-resistant bacteria reduced hospital-acquired infections among patients with central venous catheters and other devices. The ABATE infection trial included 340,000 patients from 53 hospitals. The study... Read more
4th Dubai International Conference on Infectious Diseases and Vaccination (DICID)
2019 25 Apr
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The Accelerate Pheno™ system in clinical practice: fast and accurate turnaround for critical results
2018 01 Jun
Our clinical experiences of using the Accelerate Pheno™ system have greatly benefited patient care, providing earlier diagnostic certainty. Two complex sepsis cases are discussed, where the impact of rapid identification, with antibiotic sensitivities, of the causative organism from blood cultures is described. At Hampshire Hospitals NHS... Read more
Should “empiric” antibiotic therapy be considered old-fashioned?
2018 26 Mar
The Surviving Sepsis Campaign recommends starting empiric broad-spectrum antibiotics in the initial management of patients with severe sepsis and septic shock (Rhodes et al. 2017). As a consequence, many patients receive unnecessary antibiotics, exposing them to adverse events, while others might be undertreated in spite of broad-spectrum therapy... Read more
Sepsis care bundles may increase antibiotic resistance
2017 10 Oct
Previous research has shown the effectiveness of care bundles in the diagnosis and treatment of septic patients. However, a new study suggests such care protocols could lead to increased use of certain broad-spectrum antibiotics and healthcare facility-onset (HCFO) C. difficile infection (CDI) rates. The study, published in the American Journal of... Read more
Doing the Right Thing: Antibiotics Control
2016 16 Feb
A new study shows that behavioural interventions that target the competitive spirits and desire of doctors to strengthen their reputations can motivate them to reduce unnecessary antibiotic prescriptions. The study is published in The Journal of the American Medical Association. Principal investigator and senior author Jason Doctor, Director of Health... Read more
European Congress of Clinical Microbiology and Infectious Diseases 2015: Antibiotics
2015 07 Dec
The European Congress of Clinical Microbiology and Infectious Diseases , the annual meeting of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) is the most attended infectious disease conference worldwide. This year, more than 10,000 clinicians and scientists attended the congress to present and share the latest research... Read more