Search Tag: Sedative

2025 22 May

Critically ill patients on invasive mechanical ventilation often need continuous sedation to manage pain and anxiety. For decades, researchers have sought the ideal sedative for these patients.    Propofol, a lipid-based drug that enhances γ-aminobutyric acid (GABA) receptor activity, is widely used in intensive care for varying levels of se1Read more

2018 06 Mar

Results of a randomised, placebo-controlled trial showed that a low dose of the sedative dexmedetomidine given at night may prevent delirium in critically ill patients. In this study of 100 ICU patients, half of them were randomly assigned to receive intravenous dexmedetomidine; the other half were given the placebo.   The trial published online 1Read more