Search Tag: PEEP

Capnodynamic Monitoring to Assess PEEP in COVID-19

2022 02 Aug

Optimal positive end-expiratory pressure (PEEP) level during mechanical ventilation for COVID-19 pneumonia remains debated. A third of experts in a recent consensus statement supported a low-level PEEP for COVID-19-related acute respiratory failure (C-ARDS), with half of the panel remaining neutral without agreement on PEEP titration. However, the... Read more

Response to PEEP in COVID-19 ARDS With & Without ECMO

2022 05 Jul

There have been conflicting results concerning lung recruitability of COVID-19 acute respiratory distress syndrome (ARDS) and the use of techniques derived from changes in respiratory mechanics and/or gas exchange in response to positive end-expiratory pressure (PEEP) increase. Various factors may explain the heterogeneity of reports regarding recruitability... Read more

Precision Therapies for Heterogeneous ARDS Patients

2021 20 Jul

ARDS is a heterogeneous syndrome rather than a distinct disease. It is this heterogeneity that often makes it difficult to study treatments for patients with ARDS. Literature on ARDS is rife with clinical trials that do not show any mortality benefit.   Recent evidence suggests different sub-phenotypes within the heterogeneous patient population.... Read more

Association of Higher vs Lower PEEP on Mortality

2021 19 Jul

Mechanical ventilation is a life-saving strategy for critically ill patients. However, it can promote and/or exacerbate lung injury through several mechanisms, including alveolar overdistension and repetitive opening and closing of the alveoli and small airways. Positive end-expiratory pressure (PEEP) has been employed to prevent end-expiratory alveolar... Read more

Volume 20 - Issue 1, 2020

2020 19 May

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Lung Recruitment in Patients with Severe ARDS

2019 30 Aug

Acute Respiratory Distress Syndrome (ARDS) affects up to 10% of patients in the ICU. Typical symptoms of ARDS include an increase in lung weight and a reduction of aerated lung tissue. For the treatment of ARDS alveolar recruitment is key, however, this has not yet been shown to benefit severe ARDS cases. It has been suggested that lung recruitment... Read more

Mechanical Ventilation: Which Patients Benefit from High PEEP?

2017 21 Mar

Among patients with hypoxaemia after cardiac surgery, the use of an intensive alveolar recruitment strategy compared with a moderate recruitment strategy resulted in less severe pulmonary complications during the hospital stay, according to a randomised clinical trial of postoperative ventilation published in JAMA. See Also : Towards Safer Ventilation... Read more

Accurately Setting PEEP with Transpulmonary Pressure

2015 29 Oct

Choose an optimal PEEP setting with the help of the transpulmonary pressure measurement on our high-end ventilators, HAMILTON-G5 and HAMILTON-S1 .   Acute respiratory distress syndrome (ARDS) is characterized by a decrease in respiratory system compliance due to a collapsed lung and/or a decrease in chest wall compliance. When mechanical ventilation... Read more