Search Tag: LDL-C

2020 27 Jan

Lipoprotein is believed to possess pro-atherogenic, pro-thrombotic, pro-inflammatory, and pro-oxidative properties. High levels of lipoprotein have been associated with incident cardiovascular disease in population-based epidemiological analysis and in patients with coronary heart disease (CHD). There is also a linear relationship between lipoprotein...Read more

2019 23 Sep

The European Society of Cardiology’s Guideline for the Management of Dyslipidaemias was announced at ESC 2019, nine months after the publication of the 2018 ACC/AHA Multisociety Guidelines for the Management of Blood Cholesterol. A major question for healthcare professionals around the globe is: how do these two guidelines compare? What are the differences...Read more

2019 31 Aug

Despite the fact that guidelines recommend the initiation of high-intensity statin therapy in patients with acute coronary syndrome (ACS), target levels are not achieved in a large number of patients. Evolocumab, a rapidly acting, low-density lipoprotein cholesterol (LDL-C) Lowering drug had so far not been studied in the acute phase of acute coronary...Read more

2017 15 Aug

Although some investigators have considered cholesterol the cause of atherosclerosis for several decades, data from two recent studies provide clear evidence that cholesterol is the villain, according to an Editorial article to appear in The American Journal of Cardiology. The article is available online as an accepted manuscript. In 27 April,...Read more

2016 27 Sep

A study was conducted by researchers at Brigham and Women's Hospital and Harvard Medical School to evaluate the association between lowering LDL-C and relative cardiovascular risk reduction across different statin and nonstatin therapies. The study is published in JAMA . LDL-C is an established risk factor for cardiovascular disease. It is widely...Read more

2015 20 Feb

Since the 1960s, dietary guidelines have emphasised the reduction in the consumption of saturated fat for the prevention or treatment of coronary artery disease (CAD). This is mainly because saturated fat increases the level of low-density lipoproteins cholesterol in the blood thus increasing the risk for CAD. Several studies have shown this association....Read more

2014 27 Oct

According to a new study published in JAMA , genetic predisposition to elevated low-density lipoprotein cholesterol (LDL-C) is associated with narrowing of the aortic valve. The study was conducted with 35,000 participants and the findings show a causal association between LDL-C and aortic valve disease. The findings of the study are to be presented...Read more