Search Tag: Dexmedetomidine
2025 22 May
Critically ill patients on invasive mechanical ventilation often need continuous sedation to manage pain and anxiety. For decades, researchers have sought the ideal sedative for these patients. Propofol, a lipid-based drug that enhances γ-aminobutyric acid (GABA) receptor activity, is widely used in intensive care for varying levels of se1Read more
2021 21 Sep
Delirium is very common in patients who undergo major cardiac and non-cardiac surgery. Delirium is associated with postoperative mortality, postoperative cognitive dysfunction, increased length of stay in the hospital and postoperative complications and morbidity. A study was conducted to investigate the effect of perioperative administration 1Read more
2021 22 Feb
During the question/answer session, Prof Vito Marco Ranieri discussed some important questions with Prof Salvatore Maurizio Maggiore and Prof Boris Jung regarding sedation regimen, respiratory muscle paralysis, sedation in COVID-19 patients specifically and how it is different from other regular ICU patients. Ranieri: What is your op1Read more
2019 30 May
Dexmedetomidine is used to sedate patients while maintaining a certain degree of sustainability. The use of dexmedetomidine is known to reduce the duration of mechanical ventilation and delirium among patients in the intensive care unit (ICU). However, its use as the sole sedative agent in patients undergoing mechanical ventilation has not been st1Read more
2018 06 Mar
Results of a randomised, placebo-controlled trial showed that a low dose of the sedative dexmedetomidine given at night may prevent delirium in critically ill patients. In this study of 100 ICU patients, half of them were randomly assigned to receive intravenous dexmedetomidine; the other half were given the placebo. The trial published online 1Read more
2016 30 Nov
Delirium is a common complication in intensive care unit (ICU) patients and its occurrence is associated with worse outcome (Inouye et al. 2014; Abelha et al. 2013). Sleep disturbances are considered one of the important risk factors of delirium development (Flink et al. 2012). Recent evidence shows that dexmedetomidine, either at sedative or no1Read more