Search Tag: Angiotensin II

Sepsis

Angiotensin-ii-in-critically-ill-patients

2023 22 Aug

In December 2017, angiotensin II (ATII) intravenous infusion gained approval in the U.S. for treating septic or other distributive shock in adults. This approval was based on results from a phase II clinical trial which showed higher mean arterial pressure in septic shock patients on norepinephrine, who were randomly assigned to titrated ATII compared...Read more

ICU Management

Angiotensin-ii-in-post-cardiopulmonary-bypass-vasoplegia-the-experience-so-far

2020 14 Sep

Post cardiopulmonary bypass vasoplegia is common, and associated with poor outcomes. Traditional management strategies involving escalating doses of catecholamines, vasopressin and adjuncts such as methylene blue and hydroxycobalamin or ascorbic acid have not shown promising results. Since ACE enzyme dysfunction, high serum renin and low endogenous...Read more