Search Tag: Alzheimer’s disease
Focused-ultrasound-and-the-brain
2014 08 Nov
Why is high-intensity focused ultrasound being explored to treat the brain? For a number of brain disorders focused ultrasound (FUS) will represent a treatment that is either superior to best current therapy, or fulfils an unmet clinical need. The driving factor is a validation of the technology. It doesn’t take an enormous leap of faith to appreciate...Read more
Rsna-2014-an-imaging-biomarker-of-alzheimer-s-disease
2014 01 Dec
Based on findings of a new study, changes in brain connections visible on MRI could represent an imaging biomarker of Alzheimer's disease, the most common form of dementia. For this study, researchers examined the brain's structural connectome, a map of white matter tracts that carry signals between different areas of the brain. "The structural connectome...Read more
Healthy-heart-could-prevent-alzheimer-s-disease
2015 05 Mar
A healthier heart could prevent Alzheimer's disease, according to a new study associating heart function with the development of dementia and Alzheimer's disease. Participants with decreased heart function, measured by cardiac index, were two to three times more likely to develop significant memory loss over the follow-up period. "Heart function could...Read more
Imaging-test-may-identify-biomarker-of-alzheimer-s-disease
2015 27 May
A new study published in Radiology reveals that degeneration of the brain's white matter may be an early marker of specific types of Alzheimer’s disease (AD), including early-onset AD. Researchers used diffusion tensor imaging (DTI) to assess the white matter tracts in 53 patients with three types of AD: early-onset AD and two atypical types of AD...Read more
Brain-imaging-boosts-efforts-to-lower-alzheimer-s-risk
2015 08 Jun
A report published in American Journal of Neuroradiology (AJNR) discusses how cognitive decline can be identified early and prevented by applying quantitative brain imaging techniques. Amidst growing evidence that neurodegenerative diseases alter brain structures, use of quantitative brain imaging is gaining popularity among clinicians as this helps...Read more
Cell-density-unchanged-as-brain-shrinks-with-age
2015 16 Jun
Using a powerful 9.4-Tesla MRI — the first of its kind for human imaging — researchers at the University of Illinois at Chicago have obtained the most detailed MRI images of the brain so far to show that while the brain shrinks with age, brain cell density remains constant. The findings are reported in the journal NMR in Biomedicine . The 9.4-Tesla...Read more
Insulin-resistance-increases-risk-for-alzheimer-s-disease
2015 28 Jul
An imaging study finds a strong association between insulin resistance and lower brain glucose metabolism in a group of late middle-age adults at risk for Alzheimer's disease (AD). The findings are published online in JAMA Neurology. Insulin resistance, broadly defined as reduced tissue responsiveness to the action of insulin, is common in people who...Read more
Cardiovascular-risk-factors-may-predict-alzheimer-s-disease
2015 28 Jul
An imaging study shows that specific cardiovascular risk factors, such as alcohol use, smoking, obesity and diabetes, correlate with smaller regional brain volumes that may be early indicators of Alzheimer’s disease and dementia. The findings are reported in the journal Radiology . Previous studies have linked cardiovascular risk factors and cognitive...Read more
See-through-brains-ready-for-study
2015 18 Sep
A new technique for creating transparent tissue has enabled Japanese researchers to visualise brain anatomy in 3D, giving them new insights into Alzheimer's disease plaques. "While Superman's x-ray vision is only the stuff of comics, our method, called Sca/eS, is a real and practical way to see through brain and body tissue," says lead scientist Atsushi...Read more
Heart-failure-the-alzheimer-s-disease-of-the-heart
2018 15 May
Desmin is a protein found in the cell’s “skeleton,” or supporting structure, and is known as intermediate filaments. New Johns Hopkins-led research shows desmin protein clumps appear to accumulate in the diseased hearts of mice and people with heart failure. The mechanism is similar to how protein clumps build up in the brain in people with some...Read more
New-mri-technique-for-detecting-alzheimer-s-disease
2018 18 Jul
Researchers in Spain have developed a new contrast agent for magnetic resonance imaging (MRI) based on functionalised magnetic nanoparticles that could work as a biomarker for early diagnosis of Alzheimer’s disease. Their work could pave the way for new studies that develop methods of early and noninvasive diagnosis of this neurodegenerative disease. ...Read more
Top-target-treatments-infographic
2019 22 May
Top target treatments and application of personalised medicine in healthcare Read more
Retinal-imaging-biomarker-for-early-alzheimer-s-detection
2019 19 Nov
Alzheimer’s disease (AD) is difficult to detect primarily because of the lack of measurable indicators – or biomarkers – before patients exhibit symptoms of this form of dementia. However, damage to the brain occurs years before AD is already symptomatic and advanced. New research from the University of Minnesota has looked into a promising...Read more
Rsna-2019-focused-ultrasound-may-open-door-to-alzheimer-s-treatment
2019 03 Dec
The blood-brain barrier (BBB) is a network of blood vessels and tissues that protects the brain from foreign substances. BBB poses a challenge to scientists working on new treatments because it also blocks potentially therapeutic drugs from reaching targets inside the brain. You might also like: PET Imaging Tool Measures Synaptic...Read more
Ecr2020-the-invisible-in-alzheimers
2020 17 Jul
Scientists, researchers and clinicians have spent decades trying to find a cure for Alzheimer's disease (AD). In a session at #ECR2020 Digital Congress, imaging experts talked about Alzheimer's disease and neurodegeneration: visualising the invisible. Lydiane Hirschler and Meike Venooij of the Netherlands and Javier Arbizu of Spain showed how...Read more
Rsna20-anxiety-associated-with-faster-onset-of-alzheimers-disease
2020 30 Nov
Anxiety is associated with an increased rate of progression from mild cognitive impairment to Alzheimer's disease, according to a study being presented at the annual meeting of the Radiological Society of North America (RSNA). Alzheimer's disease represents a major public health crisis worldwide. The number of deaths from the disease has more than...Read more
Ai-detects-early-alzheimers-disease-with-nearly-100-accuracy
2021 04 Oct
Mild cognitive impairment (MCI) often precedes Alzheimer’s disease. Functional MRI (fMRI) can capture subtle signs of MCI, but interpretation is difficult. KTU researchers developed an AI that identified MCI in a small study (25 subjects). Mild cognitive impairment (MCI) is one of the first signs of Alzheimer’s disease (AD). Researchers...Read more