Search Tag: Alzheimer’s disease
RSNA 2019: Focused Ultrasound May Open Door to Alzheimer's Treatment
2019 03 Dec
The blood-brain barrier (BBB) is a network of blood vessels and tissues that protects the brain from foreign substances. BBB poses a challenge to scientists working on new treatments because it also blocks potentially therapeutic drugs from reaching targets inside the brain. You might also like: PET Imaging Tool Measures Synaptic... Read more
Retinal Imaging Biomarker for Early Alzheimer's Detection
2019 19 Nov
Alzheimer’s disease (AD) is difficult to detect primarily because of the lack of measurable indicators – or biomarkers – before patients exhibit symptoms of this form of dementia. However, damage to the brain occurs years before AD is already symptomatic and advanced. New research from the University of Minnesota has looked into a promising... Read more
Top Target Treatments infographic
2019 22 May
Top target treatments and application of personalised medicine in healthcare Read more
New MRI technique for detecting Alzheimer’s disease
2018 18 Jul
Researchers in Spain have developed a new contrast agent for magnetic resonance imaging (MRI) based on functionalised magnetic nanoparticles that could work as a biomarker for early diagnosis of Alzheimer’s disease. Their work could pave the way for new studies that develop methods of early and noninvasive diagnosis of this neurodegenerative disease. ... Read more
Heart failure: the Alzheimer’s disease of the heart?
2018 15 May
Desmin is a protein found in the cell’s “skeleton,” or supporting structure, and is known as intermediate filaments. New Johns Hopkins-led research shows desmin protein clumps appear to accumulate in the diseased hearts of mice and people with heart failure. The mechanism is similar to how protein clumps build up in the brain in people with some... Read more
See-through Brains Ready for Study
2015 18 Sep
A new technique for creating transparent tissue has enabled Japanese researchers to visualise brain anatomy in 3D, giving them new insights into Alzheimer's disease plaques. "While Superman's x-ray vision is only the stuff of comics, our method, called Sca/eS, is a real and practical way to see through brain and body tissue," says lead scientist Atsushi... Read more
Cardiovascular Risk Factors May Predict Alzheimer’s Disease
2015 28 Jul
An imaging study shows that specific cardiovascular risk factors, such as alcohol use, smoking, obesity and diabetes, correlate with smaller regional brain volumes that may be early indicators of Alzheimer’s disease and dementia. The findings are reported in the journal Radiology . Previous studies have linked cardiovascular risk factors and cognitive... Read more
Insulin Resistance Increases Risk for Alzheimer's Disease
2015 28 Jul
An imaging study finds a strong association between insulin resistance and lower brain glucose metabolism in a group of late middle-age adults at risk for Alzheimer's disease (AD). The findings are published online in JAMA Neurology. Insulin resistance, broadly defined as reduced tissue responsiveness to the action of insulin, is common in people who... Read more
Cell Density Unchanged as Brain Shrinks With Age
2015 16 Jun
Using a powerful 9.4-Tesla MRI — the first of its kind for human imaging — researchers at the University of Illinois at Chicago have obtained the most detailed MRI images of the brain so far to show that while the brain shrinks with age, brain cell density remains constant. The findings are reported in the journal NMR in Biomedicine . The 9.4-Tesla... Read more
Brain Imaging Boosts Efforts to Lower Alzheimer's Risk
2015 08 Jun
A report published in American Journal of Neuroradiology (AJNR) discusses how cognitive decline can be identified early and prevented by applying quantitative brain imaging techniques. Amidst growing evidence that neurodegenerative diseases alter brain structures, use of quantitative brain imaging is gaining popularity among clinicians as this helps... Read more