Search Tag: ICU
Delirium Subtypes in Adult ICUs
2020 19 Feb
Delirium is a common problem in patients admitted to the intensive care unit and is associated with increased length of hospital stay, high mortality and long term cognitive impairment. Delayed diagnosis can often make things worse. Delirium is known to fluctuate in its presentation and its severity can also vary. Delirium is generally classified... Read more
Optimal Approach to Fluid Resuscitation for Patients in Shock
2020 03 Feb
Initial fluid resuscitation practices for patients with haemodynamic shock remain controversial. There is significant variability in these practices, and the impact of this is still poorly understood. Overall, non-patient-centred resuscitation practices, conflicting treatments, variability, and failure to meet targets for initial resuscitation are... Read more
PEPTIC Trial: Preventing Stress Ulcers in ICU Patients
2020 26 Jan
Approximately 2.5% of adults acutely admitted to an ICU develop upper gastrointestinal bleeding. 70% of these patients are prescribed stress ulcer prophylaxis. Proton pump inhibitors are the most commonly prescribed drugs as they reduce bleeding risk. However, there are some clinicians who prescribe histamine-2 receptor blockers. But this practice... Read more
Using Biomarkers for Mortality Prediction in Patients With Sepsis
2019 23 Nov
Sepsis has always carried high mortality. Even today, with all the latest technology and newer antibiotics, sepsis continues to be a major risk factor for death. It is important to understand that the earlier sepsis is diagnosed and treated, the better the prognosis. Each year, nearly 6 million people die of sepsis in the US. Because of its aggressive... Read more
Cognitive Impairment After ARDS
2019 22 Nov
Acute respiratory distress syndrome (ARDS) is a serious disorder that causes severe hypoxia requiring mechanical ventilation. It affects approximately 200,000 patients in the US each year, accounting for 10% of ICU admissions and a mortality risk of 25-40%. In many cases, patients also develop dysfunction of other organs that leads to high morbidity... Read more
Machine Learning to Predict Severe Sepsis and Septic Shock
2019 21 Oct
Sepsis is a major cause of death among hospitalised patients. It affects nearly 6% of all admissions and results in in-hospital mortality of greater than 15%. Early detection could reduce mortality, as it would result in the timely implementation of evidence-based interventions. Clinical researchers have developed and implemented a machine-learning... Read more
Challenges in the Management of the Critically Ill Patient
2019 26 Sep
Interview with Massimo Antonelli, Professor of Intensive Care and Anaesthesiology, Università Cattolica del Sacro Cuore, Rome, Italy Massimo Antonelli is a Professor of Intensive Care and Anesthesiology at the Università Cattolica del Sacro Cuore, Rome, Italy. He serves as the Director of the Dept. of Anesthesiology and Intensive Care and Emergency... Read more
Machine-Learning-Based Prediction Models for AKI
2019 23 Aug
Acute Kidney Injury (AKI) is a common occurrence for critically ill patients in the ICU, and its early diagnosis has proven to be challenging. The accuracy of the online, machine-learning-based prediction model, AKIpredictor , was analysed for its use in a clinical setting. The study, which took place over five ICUs in Belgium, compared the predictions... Read more
Effects of Sedatives and Opioids on Patient Ventilator Asynchrony
2019 09 Jul
Patient-ventilator asynchrony is frequent during invasive mechanical ventilation. If patient-ventilator interaction is poor, it can prolong the duration of mechanical ventilation and can also result in longer ICU and hospital stay as well as increased mortality. It is thus important to optimise patient-ventilator interaction. There are many factors... Read more
Nighttime Intensivist Staffing
2019 03 Jul
The work hours and sleep schedules of physicians who have completed training have seldom been studied. But there is ample evidence that suggests that sleep deprivation can cause errors in decision-making even in easy and familiar circumstances. Keeping in mind that the critical care setting is usually quite stressful, long working hours and sleep... Read more