Avreo, Inc. was founded in 1997 as Riptide Technologies. The goal of the fledgling company was to apply the speed and ease of navigating the Internet to the cumbersome task of navigating clinical information in unrelated and often unorganized hospital computer systems.

The focus of the company shifted from mere image presentation to developing a system that would integrate the myriad paper-based elements, found in typical clinical workflow, into a single, end-to-end integrated e-system. Development began on a revolutionary, flexible, component-based Web solution for Radiology.