Nikons new N-SIM microscopy system can produce nearly two times the resolution of conventional optical microscopes by combining Structured Illumination Microscopy technology licensed from UCSF and based on the world renowned Eclipse Ti research inverted microscope with Nikons legendary CFI Apo TIRF 100x oil objective lens (N.A. 1.49), developed using unique optical technologies and manufacturing techniques. N-SIM also delivers the fastest imaging capability in the industry, with a time resolution of 0.6 sec/frame.