This guideline is aimed to explain the techniques and applications that could be applied for ARZZT intramedullary locked nail for humerus and it would be recommended for use by Orthopedic and Trauma Surgeons for humerus fracture treatment. The recommendations for use are not to be intended to interfere with the surgeon's experience or the specific needs of each patient, according to the internal splint biomechanics principles for treatment of humerus shaft or proximal fractures.