Efficacy and Safety of Tirzepatide
- Cardio
- 26/03/2024
As a general marker of overall health status, few tests carry greater predictive weight then Homocysteine. The amount of Homocysteine in your blood is one of the best independent indicators of how healthy you are.
Axis-Shield launched the first immunoassay for Homocysteine and we are still at the forefront of promoting this vital marker with our Enzymatic assay for use on laboratory clinical chemistry platforms.
Simple and easy to use yet highly accurate and precise, our reagents come in multiple pack sizes to suit any laboratory from occasional use to high-throughput.
Part Number: FHRWR100
Method: Enzymatic
Description: 2 liquid-stable reagents, 2 calibrators
Intended Use
The Liquid Stable (LS) 2-Part Enzymatic Homocysteine assay is intended for in vitro quantitative determination of total homocysteine in human serum and plasma.
Assay Principle
In the Axis-Shield Enzymatic Homocysteine assay, bound or dimerised homocysteine (oxidised form) is reduced to free homocysteine, which then reacts with serine catalysed by cystathionine beta-synthase (CBS) to form L-cystathionine. Cystathionine in turn is broken down by cystathionine beta-lyase (CBL) to form homocysteine, pyruvate and ammonia. Pyruvate is then converted by lactate dehydrogenase (LDH) to lactate with NADH as coenzyme. The rate of NADH conversion to NAD is directly proportional to the concentration of homocysteine.
Loading...