Though the use of the iontophoresis device is limited depending on the molecular weight and molecular structure of the drug and the condition of the epithelium through which the drug will be injected, fluoride application on dental hard tissue, local infiltration of Udocaine for dental or dermatotogical treatment, transdermal admrstration of vitamin for healthy skin and topical administration of drugs which may cause serious s»de effects if they were administered systematically for example oral administration of antifungal drugs to cure athlete s foot. By localizing the treatment site, iontophoresis minimizes side effects. Dental Fluoride Application Fluoride application should be performed once a year for 3 minutes for infants up to three years, starting from the weaning period. The use of an iontophoresis device has some shortcomings, such as the need to handle saliva accumulation. Using both a single-use fluonde patch and a silicone tray appropriate for the size of the oral cavity together, fluoride application can be performed sanitarily and easily for a short period of time (1 minute). Lidocame Infiltration Local infiltration of 10% Udocaine can be used to perform minor dermatological surgery (on freckles or dark spots) without causing pain from injection anesthesia in which the epithelium is perforated, causing minor injuries on the skin. Using this procedure, the procedure area can be recovered without skin injuries.