The STENTYS Self-Apposing® BMS and DES(P) stents represent a major breakthrough: they solve the stent sizing dilemma that cardiologists are confronted with when a vessel size is ambiguous or challenging. In a STEMI patient where vasoconstriction and thrombus obscure the native vessel diameter, the STENTYS stent mimics the shape and diameter of the natural artery to achieve perfect apposition, and adapts to anatomic changes during the post-AMI phase to maintain apposition. Likewise in a tapered vessel such as a bifurcation lesion, the STENTYS stent is able to adapt itself to the varying proximal and distal diameters of the vessel in order to ensure stent apposition all along the vessel wall, without the need for complex balloon techniques or kissing.