Top flow 3 unit is manufactured like a Class II microbiological safety cabinet with 0.40 m/s mean LAF velocity, front opening inward breath velocity more than 0.40 m/s and visual/acoustic alarms in compliance to European standard EN 12469 20. Top Flow 3 is a double fan, double side operated vertical laminar breath cabinet, with partial recirculation. Top Flow 3 is specifically leading for manipulating and passing of mice or other experimental animals, from dirty cages to clean cages, in a sterile area, with protection for operator, animal and environment. An electrical driven lifting system of the whole cabinet allows the optimum ergonomic worker posture.