Stat Profile Prime Plus®

Stat Profile Prime Plus®
Critical Care Analyzer

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New Technologies Simplify Use and Offer Additional Tests

Stat Profile Prime Plus is a comprehensive, whole blood critical care analyzer that combines blood gases, electrolytes, metabolites, CO-Oximetry, and 32 calculated results in a simple, compact analyzer. Prime Plus combines maintenance-free, component cartridge technology for sensors and reagents with patented, new, maintenance-free, and non-lysing whole blood CO-Oximetry technology.

Prime Plus results are produced rapidly, a complete test menu panel in about one minute, and are combined with bidirectional connectivity, a robust data management system, and comprehensive cybersecurity protection.


Nova MicroSensor Card Technology



Most comprehensive critical care menu 
PO2   PCO2   pH   Hct   tHb   Na   Cl   K   iCa   TCO2   iMg   Glu   Lac   Urea (BUN)    Creat   SO2%   O2Hb   COHb    MetHb    HHb  

  • All Stat Profile Prime Plus biosensors use proven Nova technology in a miniaturized, maintenance-free sensor card format.
  • Nova MicroSensor cards combine all 20 whole blood assays including CO-Oximetry.


Important New Assays



Urea (BUN), Creatinine and eGFR
Over 50% of patients admitted to the ICU will develop some stage of acute kidney injury (AKI).1 Stat Profile Prime Plus is the only blood gas analyzer to provide whole blood urea (BUN) and creatinine (plus eGFR) test options for rapid assessment of kidney function.

Ionized magnesium (iMg)

Disruptions in the balance of iMg, Na, K, and iCa can cause cardiac arrhythmias, reduced cardiac contraction, and cardiac arrest. Prime Plus is the only blood gas analyzer to provide a comprehensive profile of electrolytes including iMg.


New Disposable CO-Oximetry Technology Eliminates Maintenance

Prime Plus incorporates a new, patented multi-wavelength optical system that scans a continuous spectrum of optical wavelengths to enable a comprehensive CO-Oximetry panel result without lysing the sample. The optical components in contact with blood are contained in the disposable sensor card.

  • Cleaning and deproteinising are completely eliminated.
  • Lysing and all its required mechanical components are eliminated, as are lysing and deproteinising reagents. This improves reliability and reduces maintenance and costs.

CO-Oximetry test menu
O2Hb     COHb     MetHb     HHb      tHb     


Fast Stat Results

Prime Plus’s exceptional throughput easily handles the high sample workload of a busy critical care setting. Prime Plus delivers a 20-test critical care profile in about one minute. Competitors’ analyzers can require up to four minutes, even with fewer tests reported.


Clot Protection

Prime Plus’s unique Clot Block sample flow path protects sensor cards from blood clot blockages.


Bidirectional Connectivity Patient Management

NovaNet bidirectional middleware for all Nova connected devices
NovaNet ensures timely, accurate capture of Nova analyzer test results for clinicians and managers to retrieve wherever and whenever needed. Also included is comprehensive cybersecurity protection and encryption that provides protection against attempts to access a hospital's network. 



Automated, True Liquid QC



Liquid QC provides the only reliable test of analyzer performance
United States federal government regulations and many international government regulations have eliminated electronic equivalent QC and are requiring true liquid QC.2


Automated QC complies with U.S. CLIA, German RiLiBAK, and other international QC requirements
QC cartridges contain a 30-day supply of liquid QC material. Controls are run automatically at user-selected intervals. Prime Plus quality controls:

  • Are comprised of a similar matrix to that of patient samples.
  • Are treated in the same manner as patient samples.
  • Follow the exact sample pathway as patient samples, from sample probe to waste container.
  • Challenge all analytical phases of testing.
  • Challenge testing at patient low, normal, and high value ranges.

Supplemental Quality Monitoring (SQM)

Prime Plus provides an automated electronic quality monitoring supplement to liquid QC. SQM continuously monitors the status and performance of all analytical components (including sensors, reagents, calibrators, sample integrity, software, and electronics), providing real-time, sample-to-sample assurance of correct performance.




Stat Profile Prime Plus® Specifications




Compact Size

Dimensions for Prime Plus, including CO-Oximetry and bidirectional connectivity:


Other Features
Full color, 10.1-inch touchscreen, multilingual, QC statistics, onboard data management, automatic sampler, integrated capillary adapter, optional barcode scanner, QC data storage, optional mobile cart with UPS

MicroSensor Card
60 µL Sample Volume

Electrical Power Requirement
< 90 Watts

Acceptable Samples
Whole blood (heparinized), arterial, venous, mixed venous
135 µL Sample draw requirement

Communication Protocols
ASTM, HL7, or POCT01-A2 connectivity formats

200 Prospect Street,
Waltham, Massachusetts
MA 02454-9141
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