3D Printing on Breathing Lung

3D Printing on Breathing Lung
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A team of mechanical engineers and computer scientists at the University of Minnesota have developed a 3D printing technique that allows to print electronic sensors directly on organs that are expanding and contracting. Their work is reported in Science Advances.

 

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This breakthrough achievement builds on the team’s previous work. Two years ago they managed to print electronic tattoos directly on the skin of a moving nondeforming hand. The new in situ 3D printing system uses motion capture technology and enables more precise tracking to 3D print sensors on organs that change shape, such as the lungs or heart. The researchers printed a hydrogel-based electrical impedance tomography (EIT) sensor on a porcine lung under respiration-induced deformation.


The research suggested modelling the deformation of the target surface with the help of using a shape basis model that could be learned from a dataset of 3D scans. A set of fiducial markers tracked by a stereo camera system facilitated the accurate recovery of the surface geometry, which was then used to dynamically adapt the 3D printing toolpath in real time.

 


Process of in situ 3D printing of EIT sensor on a breathing lung. Schematic images of (A) 3D scanning of the lung surface, (B) real-time tracking of the breathing lung, (C) adaptive printing of the hydrogel ink on the breathing lung, and (D) in situ monitoring of lung deformation with the EIT sensor. (Source: Zhu et al. 2020)

 

This AI-powered system can adapt to the deformation and motion of the target surface and effectively estimate deformation in the form of a dynamic point cloud by combining ‘offline’ machine learning with ‘online’ computer vision-based tracking. The innovative design of a hydrogel-based EIT sensor for spatiotemporal mapping has several advantages, such as simplicity in sensor geometry, desirable sensing resolution and ideal mechanical compliance to soft tissues.


The authors argue that the new 3D printing technique could have many applications in surgical robotics, such as printing electrode arrays for neural interfaces and printing bioscaffolds with engineered cells for tissue regeneration.


Image credit: Zhu et al. 2020

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References:

Zhu Zh et al. (2020) 3D printed deformable sensors. Science Advances 6(25): eaba5575. http://dx.doi.org/10.1126/sciadv.aba5575

Published on : Thu, 18 Jun 2020



3D Prinitng, biomedical devices, electrical impedance tomography (EIT) sensor, surgical robotics 3D Printing on Breathing Lung

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