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LANDI-UP: Strengthening Confidence in Landiolol for Real-World ICU and Critical Care
- Journal Article
- 10/03/2026
The LANDI-UP study provides the first European real-world evidence of landiolol use in critically ill patients with supraventricular arrhythmias. This landmark multicentre observational study demonstrates that landiolol achieves effective heart rate control with minimal haemodynamic impact, confi1
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Rethinking Blood Pressure Targets in Vasodilatory Shock
- Journal Article
- 10/03/2026
Recent high-quality evidence shows that targeting higher blood pressures in all patients with vasodilatory shock is associated with increased mortality. This review highlights the need for truly personalised resuscitation strategies. Integrating an individual’s actual pre-morbid blood pressure wi1
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Treating Tissue, Not Time: Contemporary Reperfusion Strategies in Ischaemic Stroke
- Journal Article
- 10/03/2026
This article reviews contemporary evidence on reperfusion strategies in ischaemic stroke, including intravenous thrombolysis, mechanical thrombectomy, and advanced imaging-based selection, as well as their association with mortality and functional outcomes, drawing on the major randomised control1
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