Search Tag: septic shock

ICU Management

LIVES Forum Septic Shock: From The Bug To Organ Failure

2021 03 Jun

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ICU Management

Treatment of Catecholamine Refractory Hypotension in Septic Shock: Beyond First Line Vasopressor

2020 24 Nov

Hypotension during septic shock is a strong indicator of patient outcome and mortality. Arginine vasopressin is a naturally produced human hormone with vasoconstriction effect via V1 receptor activation and a short 5-20 minutes half-life and is recommended by the Surviving Sepsis Campaign guidelines to be added as a second-line vasoactive agent when... Read more

ICU Management

Advances in Sepsis Research – New Tools Against One of the Oldest Diseases?

2020 14 Sep

Sepsis and septic shock are the leading causes of death in the ICU. With an estimated mortality rate of 40-60%, septic shock is in the focus of adult critical care medicine. It is broadly accepted that intervention in the very early phase of sepsis before the complex inflammatory host response is initiated should be one major area that clinical research... Read more

ICU Management

Optimal Approach to Fluid Resuscitation for Patients in Shock

2020 03 Feb

Initial fluid resuscitation practices for patients with haemodynamic shock remain controversial. There is significant variability in these practices, and the impact of this is still poorly understood. Overall, non-patient-centred resuscitation practices, conflicting treatments, variability, and failure to meet targets for initial resuscitation are... Read more

ICU Management

VITAMINS Trial: No Significant Benefit of Vitamin C Cocktail

2020 22 Jan

Sepsis is a life-threatening condition that causes nearly one-third to half of all hospital deaths. It is also responsible for more than 5 million deaths worldwide each year. Patients with septic shock are an important subgroup of sepsis. These patients have circulatory and metabolic abnormalities that further increase their mortality risk. New treatments... Read more

ICU Management

Top ICU Stories of 2019

2019 28 Dec

As we move into 2020, here's a quick recap of our most clicked stories in ICU in 2019:  Using Biomarkers for Mortality Prediction in Patients With Sepsis A new study evaluated the prognostic value of six biomarkers at onset of sepsis in adult patients with sepsis or septic shock. Risk Factors for Frailty and Death in the ICU... Read more

ICU Management

Hydrocortisone Versus Placebo in Patients with Septic Shock

2019 01 Dec

Septic shock is a serious illness that is associated with high morbidity and mortality. A significant number of patients who develop septic shock also have a number of comorbidities that further worsens the prognosis. Over the years, many studies have been published on the benefits of corticosteroids in patients with septic shock. Most of these... Read more

ICU Management

Using Biomarkers for Mortality Prediction in Patients With Sepsis

2019 23 Nov

Sepsis has always carried high mortality. Even today, with all the latest technology and newer antibiotics, sepsis continues to be a major risk factor for death. It is important to understand that the earlier sepsis is diagnosed and treated, the better the prognosis. Each year, nearly 6 million people die of sepsis in the US.  Because of its aggressive... Read more

ICU Management

Timing of Death Among Patients With Septic Shock

2019 14 Nov

Over the last few years, many advances have been made in the critical care of patients with septic shock. Both diagnosis and treatment strategies have improved. However, the mortality rates of patients with septic shock have a bimodal distribution; some patients die within a few days from it, while others die a few weeks later from other comorbidities. ... Read more

ICU Management

Machine Learning to Predict Severe Sepsis and Septic Shock

2019 21 Oct

Sepsis is a major cause of death among hospitalised patients. It affects nearly 6% of all admissions and results in in-hospital mortality of greater than 15%. Early detection could reduce mortality, as it would result in the timely implementation of evidence-based interventions.  Clinical researchers have developed and implemented a machine-learning... Read more