Search Tag: septic shock

ICU Management

Hydrocortisone in Severe Sepsis: HYPRESS Trial Results

2016 03 Oct

The results of the first randomised controlled trial investigating the effects of adjunctive early low-dose hydrocortisone to prevent progression to shock in patients with severe sepsis presenting without shock are published in JAMA today. There were no significant differences between treatment groups with regard to mortality or length of stay in the... Read more

ICU Management

Study: Vasopressin vs. Norepinephrine in Septic Shock

2016 27 Sep

A multicentre trial investigating early use ‏of vasopressin compared to norepinephrine ‏to treat septic shock found no reduction ‏in the number of kidney failure-free days. The ‏results of the VAsopressin vs. Noradrenaline as ‏Initial therapy in Septic sHock (VANISH) trial ‏are published in JAMA (Gordon et al. 2016). ‏   Patients who had septic shock requiring... Read more

ICU Management

Sodium Selenite Administration and Procalcitonin-Guided Therapy in Severe Sepsis

2016 09 Aug

A study was conducted to determine whether high dose intravenous sodium selenite treatment and procalcitonin-guided anti-infectious therapy in patients with severe sepsis affect mortality. The findings are published in JAMA Internal Medicine. Patients with severe sepsis suffer from oxidative stress that could contribute to multiorgan failure and death.... Read more

IT Management

Algorithm Helps Predict Patients' Deadly Sepsis

2015 07 Aug

Researchers at Johns Hopkins University have developed a new computer-based method that can help clinicians identify hospital patients at risk of septic shock. The method correctly predicts septic shock in 85 percent of cases, without increasing the false positive rate from screening methods that are currently used, according to a study published in... Read more

ICU Management

New Tool for Severe Sepsis, Septic Shock Diagnosis

2015 04 Jan

A new study, published in BMC Medical Informatics and Decision Making, aimed to determine the diagnostic accuracy of an electronic alert system in detecting severe sepsis or septic shock in ED patients. The study was carried out at a tertiary academic medical centre in Saudi Arabia. The results showed high specificity and sensitivity and negative... Read more

ICU Management

Septic Shock: Readmission Rates Above Average

2014 06 Nov

Most patients now survive a hospital stay for septic shock, although 23 percent of these patients will return to the hospital within 30 days, according to a new study. The number is noticeably higher than the normal readmission rate at a large academic medical centre, researchers reported. The study findings have been published in Critical Care Medicine.Septic... Read more

ICU Management

Study: Decrease in Risk of Death Among ICU Patients With Severe Sepsis

2014 18 Mar

According to an Australian/New Zealand study, released early in JAMA to coincide with its presentation at the International Symposium on Intensive Care and Emergency Medicine, it appears that during the years 2000 to 2012, a reduction in the risk of death for critically ill patients suffering from severe sepsis or septic shock was registered. This finding... Read more

ICU Management

Researchers Identify a New Pathway that Triggers Septic Shock

2013 18 Sep

Cells called macrophages explode when bacteria enter them and trigger an immune response through a sequence of events that UNC researchers uncovered. Credit: Jon Hagar and Ine Jørgensen.The body’s immune system is set up much like a home security system; it has sensors on the outside of cells that act like motion detectors — floodlights — that click... Read more

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