Search Tag: phenotypes

ICU Management

Sepsis-in-critical-care-3

2022 16 Mar

Sepsis is a leading cause of morbidity and mortality in the intensive care unit. Nearly  14 million adults and 2.5 million children  survive sepsis each year worldwide. In addition, sepsis survivors are known to experience poor long-term outcomes and often develop functional limitations thereafter. It is thus evident that the long-term impact...Read more

ICU Management

One-sepsis-fits-all-are-there-different-phenotypes-of-sepsis-diagnostic-approaches-and-therapies

2022 16 Mar

This article presents current research results in relation to an advanced sepsis classification and their implications for new treatment options and research strategies. Introduction Through history, the definiti on and the term sepsis changed. Since Semmelweis and others formulated the thesis that sepsis was caused by a systemic reaction...Read more

IT Management

Deep-mining-reveals-omics-promise-for-cancer-biomarkers

2020 03 Mar

Harnessing the use of omics data – derived from research studies in biomedical sciences – is becoming increasingly important in advancing personalised cancer medicine. Analyses of omics data help scientists in identifying cancer genotype and phenotype, for example.     You might also like: MRI and Radiomics Predict 10-Year Breast Cancer...Read more

ICU Management

Treatment-implications-of-novel-clinical-phenotypes-for-sepsis

2019 23 May

Sepsis affects millions of individuals every year. It carries a high risk of death, even if prompt care is provided.  It has been decades, and no new therapies for sepsis have been discovered. A major barrier to progress in this area has been the overly broad definition for this syndrome. Sepsis has a vast array of clinical and biological features,...Read more

ICU Management

Phenotyping-need-to-identify-subgroups-of-ards-patients

2018 11 Dec

The consensus definitions of acute respiratory distress syndrome (ARDS) mainly rely on feasible clinical criteria, which help to group patients together for inclusion in clinical trials and for clinical management. This generates clinical and biological differences in observable patient characteristics. These differences could be used to group ARDS...Read more

ICU Management

Volume-18-issue-1-2018-1

2018 16 Mar

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ICU Management

Icu-delirium-a-distinct-indicator-of-acute-brain-injury

2018 16 Mar

More than half of ICU patients in a new study experienced delirium for long periods during their stay. Sedative-associated delirium was most common, while longer periods of hypoxic delirium and unclassified delirium were associated with worse cognitive function at follow-up one year after hospital discharge. You might also like : Sedative prevents...Read more

ICU Management

Study-icu-delirium-a-distinct-indicator-of-acute-brain-injury

2018 27 Feb

More than half of ICU patients in a newly published study experienced delirium for long periods during their stay. Sedative-associated delirium was most common, while longer periods of hypoxic delirium and unclassified delirium were associated with worse cognitive function at follow-up one year after hospital discharge. The researchers write that...Read more