Search Tag: acute-on-chronic liver failure

ICU Management

Management-of-adult-acute-and-acute-on-chronic-liver-failure-in-the-icu

2020 03 Mar

Both acute liver failure (ALF) and acute on chronic liver failure (ACLF) are associated with high morbidity and mortality. Even today, medical treatment of these two disorders has limited benefits and for those who fail to respond, the only viable treatment is a liver transplant. Both ALF and ACLF rarely occur in isolation and in most cases there is...Read more

ICU Management

Acute-on-chronic-liver-failure-criteria-for-icu-admission

2019 10 Apr

Cirrhosis is a leading cause of morbidity and mortality throughout the world. Patients with cirrhosis may develop decompensated disease with portal hypertension and functional impairment of the liver, resulting in numerous complications including infection, variceal bleeding, hepatic encephalopathy (HE), and hepatorenal syndrome (HRS). Along...Read more

ICU Management

Liver-support-in-the-intensive-care-unit-mechanism-of-action-and-science

2018 01 Jun

The idea of liver assist is extremely attractive for patients with liver failure, as the liver possesses huge capacity to regenerate. The hypothesis behind the use of extracorporeal liver assist is to enhance the regenerative environment by removing or replacing toxic molecules while the liver can regenerate. Extracorporeal liver assist devices are...Read more

ICU Management

Volume-16-issue-3-2016-1

2016 27 Sep

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ICU Management

Evolving-concepts-in-acute-on-chronic-liver-failure

2016 27 Sep

Most patients with liver cirrhosis ‏remain in a compensated stage for ‏more than 10 years, regardless of ‏the aetiology of the liver disease. The progression ‏to decompensated cirrhosis is defined by ‏the occurrence of a major complication such ‏as ascites, variceal bleeding and/or hepatic ‏encephalopathy. From here on most patients ‏will not die because...Read more

ICU Management

Esa2016-who-benefits-from-intensive-care

2016 14 Jun

When patients and families are increasingly questioning clinical decisions, facts are important when it comes to admitting patients to intensive care. It is vital that critical care physicians have good knowledge of the important prognostic indicators, and use them as foundations for their decisions to admit, said Saxon Ridley, from Glan Clwyd Hospital...Read more

ICU Management

Acute-on-chronic-liver-failure-biomarker-can-predict-mortality

2016 04 Apr

Researchers from Aarhus University Hospital and Aarhus University in Denmark have found that the biomarker CD163 can predict mortality in patients with acute-on-chronic liver failure (ACLF). The study is published in the Journal of Hepatology . Acute-on-chronic liver failure (ACLF) is a syndrome found in liver cirrhosis patients, when liver...Read more