Search Tag: acute respiratory distress syndrome
2017 19 Sep
Acute respiratory distress syndrome (ARDS) is a common condition in intensive care unit patients and remains a major concern, with mortality rates of around 30-45% and considerable long-term morbidity. In an opinion document published in the journal Critical Care, international experts review the available clinical evidence related to ventilator support...Read more
2017 07 Jun
A number of supportive therapies have reduced mortality in acute respiratory distress syndrome (ARDS), including lung-protective mechanical ventilation, neuromuscular blockade, and prone positioning. Fluid-conservative therapy has also increased ventilator-free days in patients with ARDS. However, the lack of success of pharmacological therapies...Read more
2017 22 May
Analysis of data from the large French CUB-REA database indicates that mortality from acute respiratory distress syndrome (ARDS) was lower in high-volume ICUs than low and moderate volume ICUs. Notably, between 2000 and 2014, among 35 ICUs in the CUB-REA registry, ICU mortality decreased despite an increase in ARDS severity. The findings were presented...Read more
2017 28 Apr
Research published today in the American Journal of Respiratory and Critical Care Medicine sheds light on the economic toll on survivors of acute respiratory distress syndrome. Nearly fifty percent of survivors who worked before they were ill were not working after a year, and lost nearly two-thirds of their annual income. The researchers estimated...Read more
2017 16 Mar
What is the path forward for treatment of acute respiratory distress syndrome (ARDS)? Is it big trials (favoured by clinical scientists) or further insight into disease physiopathology (favoured by basic scientists)? Or both? Funding resources are limited and the debate is wide open. In the post-genomic era, a new direction is needed. On 20 January 2015,...Read more
2016 24 Aug
Patients who survive acute respiratory distress syndrome experience low quality of life at one year after intensive care unit (ICU) admission, and experience high associated post-hospital healthcare costs, out of pocket expenses and lost earnings. Joachim Marti, Centre for Health Policy, Imperial College London, UK, and colleagues from the UK and...Read more
2016 18 Jul
Researchers from the University of Michigan (U-M) Medical School have found culture-independent evidence that the lung microbiome is enriched with gut bacteria, both in a murine model of sepsis and in patients with ARDS. In more severely critically ill patients, lung bacteria were more outnumbered by the misplaced gut bacteria. The researchers conclude...Read more
2016 17 May
Results of a trial of helmet-based ventilation have shown that using a transparent air-tight helmet instead of a facemask helped critically ill patients breathe better and reduced their need for mechanical ventilation. In the trial, patients who were treated with helmet ventilation spent less time in the intensive care unit and lower mortality. The...Read more
2016 03 May
The recent publication of the results from the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG SAFE) study has prompted a rejoinder from Jesús Villar, CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Spain and colleagues Marcus J. Schultz and Robert M. Kacmarek, writing in Critical...Read more
2016 26 Apr
Young, female ARDS survivors, who were unemployed prior to ICU admission, are at greatest risk of psychiatric symptoms following discharge. And it is not the sickest patients with the longest ICU stay who are most at risk, according to the results from a multicentre national U.S. study, led by Johns Hopkins University researchers and published in Critical...Read more
2016 19 Apr
High-frequency oscillation ventilation does not reduce hospital and 30-day mortality in acute respiratory distress patients, compared to conventional mechanical ventilation. These are the findings of the 2016 updated Cochrane Systematic Review. The systematic review, by Sachin Sud, Trillium Health Center, University of Toronto, Division of Critical...Read more
2016 11 Mar
Improved Outcomes of Immunocompromised Patients Admitted to the ICU Immunocompromised patients, who include patients with haematological malignancies (HMs), solid tumours, solid-organ transplants, human immunodeficiency virus (HIV) or long-term corticosteroid use, are increasingly admitted to intensive care units (ICUs). Their survival has improved...Read more
2016 11 Mar
Acute respiratory distress syndrome (ARDS) seems to be underrecognised, under-treated and associated with a high risk of mortality, according to the results of the ESICM LUNG-SAFE observational study, published in JAMA . Speaking to ICU Management & Practice, John G. Laffey , MD, MA, of the Departments of Anesthesia and Critical Care Medicine,...Read more
2016 22 Feb
Acute respiratory distress syndrome (ARDs) seems to be under-recognised, under-treated and associated with a high risk of mortality, despite the ARDS Berlin definition and good evidence on treatments. The results of the ESICM LUNG-SAFE observational study are published in JAMA. Speaking to ICU Management, John G. Laffey , MD, MA, of the Departments...Read more
2014 23 Oct
According to the largest study to date of mortality trends in patients with acute respiratory distress syndrome (ARDS), advances in critical care medicine played a major role in reducing the rate of mortality over a sixteen year period. The study has been published in the journal CHEST and will be presented at Chest 2014, the annual meeting of the...Read more