Search Tag: acute respiratory distress syndrome

ICU Management

Phenotyping: need to identify subgroups of ARDS patients

2018 11 Dec

The consensus definitions of acute respiratory distress syndrome (ARDS) mainly rely on feasible clinical criteria, which help to group patients together for inclusion in clinical trials and for clinical management. This generates clinical and biological differences in observable patient characteristics. These differences could be used to group ARDS... Read more

ICU Management

Are 'sniffer systems' effective in detecting ARDS?

2018 11 Dec

Acute respiratory distress syndrome (ARDS) results in substantial mortality but remains underdiagnosed in clinical practice. For this reason, automated “sniffer” systems that analyse electronic records have been developed to assist clinicians with ARDS diagnosis. However, a new systematic review found that these sniffer tools had moderate to high predictive... Read more

ICU Management

Closer monitoring needed for patients with 'mild' ARDS

2018 04 Dec

If you landed here from ICU Highlights e-newsletter you may be looking for New protocol for respiratory infectious disease diagnosis in ICU. Hospital mortality in acute respiratory distress syndrome (ARDS) is approximately 40 percent, but mortality and trajectory in “mild” ARDS – classified only since 2012 – are unknown. A new study finds that... Read more

ICU Management

Alleviating inflammation: new inhibitor could treat ARDS in future

2018 20 Nov

A newly discovered OGG1 inhibitor has been found to decrease lung inflammation in mice and could in future treat acute respiratory distress syndrome (ARDS), sepsis and autoimmune diseases. The six-year study, by an international team of researchers, is published in Science . The research shows that the OGG1 protein, which is involved in repairing... Read more

ICU Management

Study: Air pollution associated with ARDS hospitalisation in over 65s

2018 01 Jun

A comparison of hospital admissions of patients over 65 and air pollution in the USA has found an association between exposure to pollutants and admission for acute respiratory distress syndrome (ARDS). The study was presented at the annual meeting of the American Thoracic Society.   The researchers analysed data by zip code from nearly 30 million... Read more

ICU Management

ARDS reclassification - the debate continues

2018 15 May

A new analysis of data from patients enrolled in high-quality ARDSnet trials showed no difference between patients with moderate-severe and mild-moderate ARDS in terms of mortality, even though there were differences in rapid resolution of ARDS, ventilator-free days and ICU-free days. The research is published online in Annals of the American Thoracic... Read more

ICU Management

Volume 18 - Issue 1, 2018

2018 16 Mar

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ICU Management

CO2 in the critically ill

2018 16 Mar

CO 2 exerts potent effects on lung biology that could be clinically relevant in critically ill patients, in particular those with acute respiratory distress syndrome (ARDS). The impact of hypercapnia on outcome in these patients is yet to be determined. The physiological effects of hypercapnia are increasingly well understood, but the literature... Read more

ICU Management

ARDS, delirium and antipsychotic use reviewed

2018 21 Feb

Acute respiratory distress syndrome (ARDS) often requires prolonged and complicated hospital courses putting patients at risk for intensive care unit (ICU) delirium. Antipsychotics are prescribed to decrease the severity and duration of ICU delirium; however, these drugs are associated with many adverse effects including respiratory failure. "Given... Read more

ICU Management

Making mechanical ventilation safe for ARDS

2018 08 Jan

The acute respiratory distress (ARDS) lung is usually characterised by a high degree of inhomogeneity. Indeed, the same lung may show a wide spectrum of aeration alterations, ranging from completely gasless regions, up to hyperinflated areas, explain Luciano Gattinoni, Tommaso Tonetti and Michael Quintel in an article published in the journal Critical... Read more