Search Tag: acute respiratory distress syndrome

ICU Management

Making mechanical ventilation safe for ARDS

2018 08 Jan

The acute respiratory distress (ARDS) lung is usually characterised by a high degree of inhomogeneity. Indeed, the same lung may show a wide spectrum of aeration alterations, ranging from completely gasless regions, up to hyperinflated areas, explain Luciano Gattinoni, Tommaso Tonetti and Michael Quintel in an article published in the journal Critical... Read more

ICU Management

Can we improve the reliability of ARDS diagnosis?

2018 08 Jan

Failure to reliably diagnose ARDS, or acute respiratory distress syndrome, could lead to underrecognition and undertreatment in clinical practice. New research shows the reliability of the Berlin ARDS definition is "moderate," driven primarily by differences in chest imaging interpretation. The study is in press in the journal CHEST.The 2012 revision... Read more

ICU Management

After 50 years, ARDS stuck in the past?

2017 14 Nov

The acute respiratory distress syndrome (ARDS) was first reported in 1967. Upon the occasion of its 50th birthday, ARDS is due for a midlife crisis, says Dr. Robert P. Dickson, of the Division of Pulmonary and Critical Care Medicine, University of Michigan Health System. "In our era of molecular medicine, ARDS seems a bit stuck in the past," he writes... Read more

ICU Management

Driving pressure and hospital mortality in non-ARDS patients

2017 24 Oct

According to researchers in Canada, driving pressure was not associated with hospital mortality in a cohort of mechanically ventilated, critically ill patients without Acute Respiratory Distress Syndrome (ARDS), in whom compliance was also not associated with mortality. They say their findings published in the journal CHEST need to be replicated in... Read more

ICU Management

Respiratory support in ARDS: an expert opinion

2017 19 Sep

Acute respiratory distress syndrome (ARDS) is a common condition in intensive care unit patients and remains a major concern, with mortality rates of around 30-45% and considerable long-term morbidity. In an opinion document published in the journal Critical Care, international experts review the available clinical evidence related to ventilator support... Read more

ICU Management

Clinical Trials in ARDS - Challenges and Opportunities

2017 07 Jun

A number of supportive therapies have reduced mortality in acute respiratory distress syndrome (ARDS), including lung-protective mechanical ventilation, neuromuscular blockade, and prone positioning. Fluid-conservative therapy has also increased ventilator-free days in patients with ARDS. However, the lack of success of pharmacological therapies for... Read more

ICU Management

ARDS: Treat High-volume, Lower Mortality

2017 22 May

Analysis of data from the large French CUB-REA database indicates that mortality from acute respiratory distress syndrome (ARDS) was lower in high-volume ICUs than low and moderate volume ICUs. Notably, between 2000 and 2014, among 35 ICUs in the CUB-REA registry, ICU mortality decreased despite an increase in ARDS severity. The findings were presented... Read more

ICU Management

Economic Cost to Surviving ARDS, New Study

2017 28 Apr

Research published today in the American Journal of Respiratory and Critical Care Medicine sheds light on the economic toll on survivors of acute respiratory distress syndrome. Nearly fifty percent of survivors who worked before they were ill were not working after a year, and lost nearly two-thirds of their annual income. The researchers estimated... Read more

ICU Management

Volume 17 - Issue 1, 2017

2017 16 Mar

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ICU Management

ARDS and Precision Medicine

2017 16 Mar

What is the path forward for treatment of acute respiratory distress syndrome (ARDS)? Is it big trials (favoured by clinical scientists) or further insight into disease physiopathology (favoured by basic scientists)? Or both? Funding resources are limited and the debate is wide open. In the post-genomic era, a new direction is needed. On 20 January 2015,... Read more