Search Tag: acute respiratory distress syndrome

ICU Management

Clinical Trials in ARDS - Challenges and Opportunities

2017 07 Jun

A number of supportive therapies have reduced mortality in acute respiratory distress syndrome (ARDS), including lung-protective mechanical ventilation, neuromuscular blockade, and prone positioning. Fluid-conservative therapy has also increased ventilator-free days in patients with ARDS. However, the lack of success of pharmacological therapies for... Read more

ICU Management

ARDS: Treat High-volume, Lower Mortality

2017 22 May

Analysis of data from the large French CUB-REA database indicates that mortality from acute respiratory distress syndrome (ARDS) was lower in high-volume ICUs than low and moderate volume ICUs. Notably, between 2000 and 2014, among 35 ICUs in the CUB-REA registry, ICU mortality decreased despite an increase in ARDS severity. The findings were presented... Read more

ICU Management

Economic Cost to Surviving ARDS, New Study

2017 28 Apr

Research published today in the American Journal of Respiratory and Critical Care Medicine sheds light on the economic toll on survivors of acute respiratory distress syndrome. Nearly fifty percent of survivors who worked before they were ill were not working after a year, and lost nearly two-thirds of their annual income. The researchers estimated... Read more

ICU Management

Volume 17 - Issue 1, 2017

2017 16 Mar

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ICU Management

ARDS and Precision Medicine

2017 16 Mar

What is the path forward for treatment of acute respiratory distress syndrome (ARDS)? Is it big trials (favoured by clinical scientists) or further insight into disease physiopathology (favoured by basic scientists)? Or both? Funding resources are limited and the debate is wide open. In the post-genomic era, a new direction is needed. On 20 January 2015,... Read more

ICU Management

Study: ARDS Costs, Survival, QOL over One Year

2016 24 Aug

Patients who survive acute respiratory distress syndrome experience low quality of life at one year after intensive care unit (ICU) admission, and experience high associated post-hospital healthcare costs, out of pocket expenses and lost earnings.Joachim Marti, Centre for Health Policy, Imperial College London, UK, and colleagues from the UK and Canada... Read more

ICU Management

Study: Microbiome Disruption May Have Key Role in ARDS, Sepsis

2016 18 Jul

Researchers from the University of Michigan (U-M) Medical School have found culture-independent evidence that the lung microbiome is enriched with gut bacteria, both in a murine model of sepsis and in patients with ARDS. In more severely critically ill patients, lung bacteria were more outnumbered by the misplaced gut bacteria. The researchers conclude... Read more

ICU Management

Helmet-Based Ventilation Had Better Results than Facemask for ARDS Patients

2016 17 May

Results of a trial of helmet-based ventilation have shown that using a transparent air-tight helmet instead of a facemask helped critically ill patients breathe better and reduced their need for mechanical ventilation. In the trial, patients who were treated with helmet ventilation spent less time in the intensive care unit and lower mortality. The... Read more

ICU Management

ARDS Prevalence in LUNG-SAFE Study Questioned

2016 03 May

The recent publication of the results from the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG SAFE) study has prompted a rejoinder from Jesús Villar, CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Spain and colleagues Marcus J. Schultz and Robert M. Kacmarek, writing in Critical... Read more

ICU Management

Young Females At High Risk for Psych Symptoms after ARDS

2016 26 Apr

Young, female ARDS survivors, who were unemployed prior to ICU admission, are at greatest risk of psychiatric symptoms following discharge. And it is not the sickest patients with the longest ICU stay who are most at risk, according to the results from a multicentre national U.S. study, led by Johns Hopkins University researchers and published in Critical... Read more