Search Tag: Biomarkers

Reducing Sepsis Deaths

2015 21 Apr

Sepsis is a common condition whereby an infection triggers an extreme immune response, resulting in widespread inflammation, blood clotting, and swelling. Although sepsis is believed to contribute to between a third and a half of all hospital deaths, the condition remains poorly understood. Now leading doctors warn that medical and public recognition... Read more

Pancreatic Cancer: MRI Protocol for High-Risk Patients

2015 09 Apr

A magnetic resonance imaging (MRI)-based screening programme for individuals at high risk of pancreatic cancer detected pancreatic lesions in 16 of 40 (40 percent) of patients, of whom five underwent surgery, according to a study published online in JAMA Surgery . “An MRI-based protocol for the surveillance of individuals at risk for developing pancreatic... Read more

Inexpensive Innovation: Biosensing Platform Diagnoses Disease Remotely

2015 08 Apr

A quick and cost-effective means of diagnosing diseases and monitoring treatment at the point-of-care has been developed by researchers using paper and flexible substrates as biosensing materials. The new platforms have been shown to isolate and selectively detect multiple biotargets in whole blood, serum and peritoneal fluid using antibodies. The... Read more

Biomarker Predicts Burn Patients' Risk of Infection

2015 11 Feb

A Massachusetts General Hospital (MGH)-led study has shown that a set of characteristics, including differences in gene expression, may indicate which patients recovering from severe burns are at greatest risk for repeat infections. The finding is published online in Annals of Surgery . "Our approach is the first to enable the prediction of repeat... Read more

New Biomarkers That Could Predict Cardiovascular Risk

2015 05 Feb

A blood profiling technique has uncovered four new biomarkers that improve the prediction of risk for heart attack or stroke within the next 15 years. The study has been published in the journal Circulation.   The blood screening technology can help doctors identify people who would benefit from early treatment. In addition, the high-throughput... Read more

Pandora’s Box of Cancer Biomarkers

2015 24 Jan

Researchers at the University of Michigan Comprehensive Care Center have conducted a new analysis that could open the door to discovery of thousands of potential new cancer biomarkers. The researchers analysed the long non-coding RNAs (lncRNAs) - a vast portion of the human genome that has not been well-explored before. It is believed that lncRNAs... Read more

Biomarkers Linked to Kidney Damage, Death in Critically Ill

2015 19 Jan

Based on results of a new study, high levels of two novel urinary biomarkers early in critical illness correlate with adverse long-term outcomes in patients with acute kidney injury (AKI). The combination of tissue inhibitor metalloproteinase-2 (TIMP-2) and IGF-binding protein-7 (IGFBP7) can identify patients with AKI who are at greater risk of death... Read more

Quantitative Imaging: Building the Foundations

2014 08 Nov

Note : RSNA recently announced an additional $1.27 million of funding from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) to support research by the Quantitative Imaging Biomarkers Alliance (QIBA). The funding will be used towards the development of a Quantitative Imaging Data Warehouse, research to characterise the sources... Read more

Biomarker Tests Reduce Unnecessary Antibiotic Prescriptions

2014 07 Nov

On-the-spot tests for bacterial infections, which only take about three minutes to process, may help to reduce excessive use of antibiotics. Researchers in Denmark performed a systematic review showing that doctors who tested for the presence of bacterial infections were prescribing fewer antibiotics. Their findings are published online in The Cochrane... Read more

Single Blood Test To Screen For Different Types Of Cancer

2014 05 Nov

More than 800 markers have been identified in the blood of cancer patients that could potentially lead to the development of a single blood test for early detection of many cancer types. In a study conducted by the UK Early Cancer Detection Consortium (ECDC), which was presented at the National Cancer Research Institute Conference in Liverpool, researchers... Read more