Search Tag: Anakinra

ICU Management

2026 28 Jan

A recent article reports the INSPIRE trial, a study evaluating whether a precision immunotherapy strategy using the interleukin-1 (IL-1) receptor antagonist anakinra can prevent progression to organ dysfunction and death in adults hospitalised with community-acquired or hospital-acquired pneumonia who are identified as high risk by elevated presep1Read more

ICU Management

2025 22 May

Both corticosteroids and interleukin-6 receptor antagonists (IL-6ra) -  tocilizumab and sarilumab - improve survival and reduce organ support needs in hospitalised COVID-19 patients, but their comparative effectiveness is unclear. Alternative treatments may be needed due to drug access issues.    Interleukin-1 (IL-1), involved in acute infla1Read more